Substrate presentation

<p>In <a href="/facts/Molecular_biology/YgqU35ub">molecular biology</a>, substrate presentation is a biological process that activates a <a href="/facts/Protein/Jxmagu3E">protein</a>. The protein is sequestered away from its <a href="/facts/Substrate_(chemistry)/6MnaV19h">substrate</a> and then activated by release and exposure to its substrate. A <i>substrate</i> is typically the substance on which an <a href="/facts/Enzyme/DSI1Fh7y">enzyme</a> acts but can also be a protein surface to which a <a href="/facts/Ligand/6etB3qeW">ligand</a> binds. In the case of an interaction with an enzyme, the protein or organic substrate typically changes chemical form. Substrate presentation differs from <a href="/facts/Allosteric_regulation/alMRuyt9">allosteric regulation</a> in that the enzyme need not change its <a href="/facts/Protein_conformation/BptnTs9X">conformation</a> to begin <a href="/facts/Catalysis/LPBS7TQC">catalysis</a>. Substrate presentation is best described for domain partitioning at <a href="/facts/Nanoscopic_scale/hyFgwMKM">nanoscopic</a> distances (<100 nm).
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Substrate presentation open-in-new

Substrate presentation