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Reference.org
HES5
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<p>Transcription factor HES-5 is a <a href="/facts/Protein/Jxmagu3E">protein</a> that in humans is encoded by the <i>HES5</i> <a href="/facts/Gene/e1swwPY6">gene</a>. </p><p>HES5 regulates the development of the early brain by maintaining stem cell neural progenitors in the ventricular zone. HES5 expression significantly higher in <a href="/facts/Squamous_epithelium/ecKHcHC3">squamous</a> <a href="/facts/Cervical_carcinoma/99vngUyd">cervical carcinoma</a> than in CIN as well as higher in CIN than normal <a href="/facts/Cervix/qw3gl8Pq">cervical</a> <a href="/facts/Epithelium/ecKHcHC3">epithelia</a>. Human HES5 gene binds to <a href="/facts/Notch_signaling/5sVkTc0A">Notch receptor</a> and expression of HES5 decreases during cartilage differentiation. </p>