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Multilocus sequence typing
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<p>Multilocus sequence typing (MLST) is a technique in <a href="/facts/Molecular_biology/YgqU35ub">molecular biology</a> for the typing of multiple <a href="/facts/Locus_(genetics)/JcIT8wLm">loci</a>, using <a href="/facts/DNA_sequences/qAf4kTee">DNA sequences</a> of internal fragments of multiple <a href="/facts/Housekeeping_gene/jgUg3yE8">housekeeping genes</a> to characterize isolates of microbial species. </p><p>The first MLST scheme to be developed was for <i><a href="/facts/Neisseria_meningitidis/u4SqwHuc">Neisseria meningitidis</a></i>, the causative agent of meningococcal <a href="/facts/Meningitis/4m4STzJB">meningitis</a> and <a href="/facts/Septicaemia/n52bkffJ">septicaemia</a>. Since its introduction for the research of evolutionary history, MLST has been used not only for human pathogens but also for plant pathogens. </p>