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Selenomethionine
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<p>Selenomethionine (SeMet) is a naturally occurring <a href="/facts/Amino_acid/WDxYwBny">amino acid</a>. The L-selenomethionine <a href="/facts/L-enantiomer/wjPv5J3y">enantiomer</a> is the main form of <a href="/facts/Selenium/k975NApC">selenium</a> found in <a href="/facts/Brazil_nuts/eCSRJ3Vl">Brazil nuts</a>, <a href="/facts/Cereal_grains/ao2WcFdM">cereal grains</a>, <a href="/facts/Soybeans/reNwxvo2">soybeans</a>, and grassland <a href="/facts/Legumes/x6s6gVHY">legumes</a>, while <a href="/facts/Se-methylselenocysteine/27GbpPgT"><i>Se</i>-methylselenocysteine</a>, or its <a href="/facts/Transglutaminase/8fjQq01V">γ-glutamyl derivative</a>, is the major form of selenium found in <i><a href="/facts/Astragalus_(plant)/sxf73Fy6">Astragalus</a></i>, <i><a href="/facts/Allium/lWf7Fdjq">Allium</a></i>, and <i><a href="/facts/Brassica/x0L32VGA">Brassica</a></i> species. <i>In vivo</i>, selenomethionine is randomly incorporated instead of <a href="/facts/Methionine/7neydPKo">methionine</a>. Selenomethionine is readily oxidized. </p><p>Selenomethionine's antioxidant activity arises from its ability to deplete <a href="/facts/Reactive_oxygen_species/GpwSRugH">reactive oxygen species</a>. <a href="/facts/Selenium/k975NApC">Selenium</a> and <a href="/facts/Methionine/7neydPKo">methionine</a> also play separate roles in the formation and recycling of <a href="/facts/Glutathione/5bSxjusL">glutathione</a>, a key endogenous antioxidant in many organisms, including humans. </p>