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Kokko and Rector Model
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<p>The Kokko and Rector model is a theory explaining the mechanism of generation of a gradient in the <a href="/facts/Inner_medulla/wl4SDWen">inner medulla</a> of the <a href="/facts/Kidney/HBspPrv9">kidney</a>. Unlike earlier theories explaining the mechanism using counter current mechanism (as is the case in the <a href="/facts/Outer_medulla/wl4SDWen">outer medulla</a>), the driving force for salt reabsorption is stated to be urea accumulation. It has been proved that counter current mechanism cannot be the case in the <a href="/facts/Inner_medulla/wl4SDWen">inner medulla</a>, since there are no salt pumps, and the <a href="/facts/Cell_membrane/vAXSD0DT">cell membrane</a> is too <a href="/facts/Semipermeable_membrane/YxENKzn5">permeable</a> to salt. </p>