Alcohol dehydrogenase

<p>Alcohol dehydrogenases (ADH) (<a href="/facts/Enzyme_Commission_number/Y5GNLRKX">EC</a> <a href="https://enzyme.expasy.org/EC/1.1.1.1">1.1.1.1</a>) are a group of <a href="/facts/Dehydrogenase/hX7eulAz">dehydrogenase</a> <a href="/facts/Enzyme/DSI1Fh7y">enzymes</a> that occur in many organisms and facilitate the interconversion between <a href="/facts/Alcohol_(chemistry)/Y0SCTDkh">alcohols</a> and <a href="/facts/Aldehyde/xSIRkW03">aldehydes</a> or <a href="/facts/Ketone/BqQXpLo4">ketones</a> with the reduction of <a href="/facts/Nicotinamide_adenine_dinucleotide/BHdLW925">nicotinamide adenine dinucleotide</a> (NAD+) to NADH. In <a href="/facts/Human/rlcTENsr">humans</a> and many other <a href="/facts/Animal/4b8J33nd">animals</a>, they serve to break down alcohols that are otherwise toxic, and they also participate in the generation of useful aldehyde, ketone, or alcohol groups during the biosynthesis of various <a href="/facts/Metabolites/nAyywVtA">metabolites</a>. In <a href="/facts/Yeast/eGD24nfI">yeast</a>, plants, and many <a href="/facts/Bacteria/wC8xSCsU">bacteria</a>, some alcohol dehydrogenases <a href="/facts/Catalysis/LPBS7TQC">catalyze</a> the opposite reaction as part of <a href="/facts/Fermentation/rxaDr28b">fermentation</a> to ensure a constant supply of NAD+.
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Alcohol dehydrogenase open-in-new

Alcohol dehydrogenase