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Trip killer
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<p>A trip killer, also known as a hallucinogen antidote or hallucinogen antagonist, is a <a href="/facts/Drug/FFFUI9n4">drug</a> that <a href="/facts/Antidote/l9rHGlko">aborts or reduces the effects</a> of a <a href="/facts/Hallucinogen/gn35weCu">hallucinogenic</a> <a href="/facts/Drug/FFFUI9n4">drug</a> <a href="/facts/Psychedelic_experience/8uJ4ce7r">experience</a> (or 'trip'). As there are different types of hallucinogens that work in different ways, there are different types of trip killers. They can completely block or reduce the effects of hallucinogens, or they can simply provide <a href="/facts/Anxiolysis/uEWpGca9">anxiety relief</a> and <a href="/facts/Sedation/wFWEChs8">sedation</a>. </p><p>Examples of trip killers, in the case of <a href="/facts/Serotonergic_psychedelic/oyp10dgE">serotonergic psychedelics</a>, include <a href="/facts/Serotonin_receptor_antagonist/Fp9DX8oW">serotonin receptor antagonists</a>, such as <a href="/facts/Antipsychotic/7bNTg7T3">antipsychotics</a> like <a href="/facts/Risperidone/xpFEYzoF">risperidone</a> and <a href="/facts/Quetiapine/hI3hPqEH">quetiapine</a> and certain <a href="/facts/Antidepressant/N62ND3Fa">antidepressants</a> like <a href="/facts/Trazodone/ncFDxzGF">trazodone</a> and <a href="/facts/Mirtazapine/VyxPQttv">mirtazapine</a>, and <a href="/facts/Benzodiazepine/IgbJr4jy">benzodiazepines</a>, for instance <a href="/facts/Diazepam/h7lIGqkM">diazepam</a> and <a href="/facts/Alprazolam/nfMPlLFa">alprazolam</a>. </p><p>Trip killers can be used clinically to manage effects of hallucinogens, like hallucinogenic effects, anxiety, and <a href="/facts/Psychomotor_agitation/n1vWk6RD">psychomotor agitation</a>, for instance in the <a href="/facts/Emergency_department/Qo4NcDeP">emergency department</a> and in the setting of <a href="/facts/Psychedelic_therapy/mokV4INC">psychedelic therapy</a>. They are also sometimes used by <a href="/facts/Recreational_drug_use/eoBD3vKn">recreational</a> psychedelic users as a form of <a href="/facts/Harm_reduction/2cAHgTu7">harm reduction</a> to manage "<a href="/facts/Bad_trip/1PsFwQdd">bad trips</a>" or challenging experiences, for instance emotionally difficult experiences with prominent <a href="/facts/Anxiety/Geekl883">anxiety</a>. While used for harm-reduction purposes, this use of trip killers has raised concerns about <a href="/facts/Drug_safety/4v2PDxCM">safety</a> and possible <a href="/facts/Adverse_effect/vAhfbr1J">adverse effects</a>. </p>