In MVS/370 and successor versions of IBM mainframe operating systems, Start Input/Output (STARTIO) is a macro instruction and a "branch entry" for low-level device access, where the programmer is responsible for providing a list of device-specific CCWs, that is, a channel program, to be executed by I/O channels, control units and devices and a number of "exits", several of which may be immediate returns to the Input/Output Supervisor (IOS). Invokers of STARTIO must be in supervisor mode and key 0. STARTIO interfaces directly with the IOS component of MVS.