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Reference.org
Receptor theory
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<p>Receptor theory is the application of receptor models to explain drug behavior. Pharmacological receptor models preceded accurate knowledge of <a href="/facts/Receptor_(biochemistry)/tjTAC76a">receptors</a> by many years. <a href="/facts/John_Newport_Langley/wvHdk8mC">John Newport Langley</a> and <a href="/facts/Paul_Ehrlich/6XM57Clc">Paul Ehrlich</a> introduced the concept that receptors can mediate drug action at the beginning of the 20th century. <a href="/facts/Alfred_Joseph_Clark/Wz9g3mGK">Alfred Joseph Clark</a> was the first to quantify drug-induced biological responses (specifically, f-mediated receptor activation). So far, nearly all of the quantitative theoretical modelling of receptor function has centred on <a href="/facts/Ligand-gated_ion_channels/gN9RkNC2">ligand-gated ion channels</a> and <a href="/facts/G_protein-coupled_receptor/0arUMkQc">G protein-coupled receptors</a>. </p>