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Reference.org
ELAV-like protein 1
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<p>ELAV-like protein 1 or HuR (human antigen R) is a <a href="/facts/Protein/Jxmagu3E">protein</a> that in humans is encoded by the <i>ELAVL1</i> <a href="/facts/Gene/e1swwPY6">gene</a>. </p><p>The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting <a href="/facts/AU-rich_element/BHe6L1D2">AU-rich elements</a> in <a href="/facts/3%2527_untranslated_region/wB0oYfKd">3' untranslated regions</a>. One of its best-known functions is to stabilize <a href="/facts/MRNA/oUL6qxQn">mRNAs</a> in order to regulate gene expression. Various <a href="/facts/Post-translational_modification/KMUayTIc">post-translational modifications</a> of HuR influence its <a href="/facts/Subcellular/bLM9UQvy">subcellular</a> localization and stability of binding to mRNAs. </p>