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Reference.org
43S preinitiation complex
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<p>The 43S preinitiation complex (43S PIC) is a <a href="/facts/Ribonucleoprotein/S07sU6hq">ribonucleoprotein complex</a> that exists during an early step of <a href="/facts/Eukaryotic_translation/0A9ezESb">eukaryotic translation</a> initiation. The 43S PIC contains the <a href="/facts/Eukaryotic_small_ribosomal_subunit_(40S)/MGjtY3u4">small ribosomal subunit (40S)</a> bound by the initiation factors <a href="/facts/EIF1/MnQ6y8jn">eIF1</a>, <a href="/facts/EIF1AX/cV4jqbWG">eIF1A</a>, <a href="/facts/EIF3/eVazcjSL">eIF3</a>, and the <a href="/facts/EIF2/JsCGLNta">eIF2</a>-Met-<a href="/facts/TRNA/pR9T5XSl">tRNA</a>iMet-GTP ternary complex (eIF2-TC). </p>