Thiodiglycol

Thiodiglycol, or bis(2-hydroxyethyl)sulfide (also known as 2,2-thiodiethanol or TDE), is the <a href="/facts/Organosulfur_compound/sUxSSXwD">organosulfur compound</a> with the formula S(CH2CH2OH)2. It is miscible with <a href="/facts/Water/0lkXnJPK">water</a> and polar <a href="/facts/Organic_solvent/LoMPMz8S">organic solvents</a>. It is a colorless liquid. It is structurally similar to <a href="/facts/Diethylene_glycol/mFRnKswQ">diethylene glycol</a>.
Thiodiglycol is manufactured by reaction of <a href="/facts/2-Chloroethanol/J3f130Y0">2-chloroethanol</a> with <a href="/facts/Sodium_sulfide/DKu0s158">sodium sulfide</a>.
Thiodiglycol is a polar protic solvent. It is used as a <a href="/facts/Solvent/LoMPMz8S">solvent</a> in a variety of applications ranging from dyeing <a href="/facts/Textile/PJrVeM5S">textiles</a> to <a href="/facts/Ink/Y7Wj0YQS">inks</a> in some <a href="/facts/Ballpoint_pen/svhmmyys">ballpoint pens</a>. In chemical synthesis, it is used as a building block for protection products, dispersants, <a href="/facts/Fiber/ttkxAFBu">fibers</a>, <a href="/facts/Plasticizer/RjzuplRY">plasticizers</a>, rubber accelerators, <a href="/facts/Pesticide/Uhf4KnwJ">pesticides</a>, <a href="/facts/Dye/a1NSlcsG">dyes</a>, and various other organic chemicals. In the manufacture of <a href="/facts/Polymer/eF32E50K">polymers</a>, it is used as a <a href="/facts/Chain_transfer_agent/G2uQ7Qay">chain transfer agent</a>. As an <a href="/facts/Antioxidant/4TG4MQ83">antioxidant</a>, it is used as an additive in <a href="/facts/Lubricant/9PXISDwU">lubricants</a>.
Thiodiglycol is used as a <a href="/facts/Mounting_medium/DaM2Lrac">mounting medium</a> in <a href="/facts/Microscopy/GpHlElDS">microscopy</a>. The ability to vary the <a href="/facts/Refractive_index/yjkzvgeE">refractive index</a> of the medium by varying the concentration of TDE in an aqueous solution, plus its relative lack of toxicity makes it highly desirable for such use. The refractive index of the solution can be varied anywhere from near that of water (1.333) to that of glass (1.518).
Thiodiglycol is a <a href="/facts/Chemical_Weapons_Convention/eP3Vsv5o">Chemical Weapons Convention</a> <a href="/facts/List_of_Schedule_2_substances_(CWC)/1UE0dt9h">schedule 2 chemical</a> used in the production of sulfur-based <a href="/facts/Mustard_gas/e3qWU2Qp">mustard gases</a>. Thiodiglycol is also a product of the <a href="/facts/Hydrolysis/JTvwIHPs">hydrolysis</a> of the "mustard gas" <a href="/facts/Bis(2-chloroethyl)sulfide/3omcrvFK">bis(2-chloroethyl)sulfide</a> and can be detected in the <a href="/facts/Urine/oNUYVtvX">urine</a> of casualties.

Thiodiglycol open-in-new

Thiodiglycol