Chlordiazepoxide

Chlordiazepoxide hydrochloride, sold under the brand name Librium is a <a href="/facts/Sedative/JWzvq66P">sedative</a> and <a href="/facts/Hypnotic/0SBVYkMe">hypnotic</a> medication of the <a href="/facts/Benzodiazepine/IgbJr4jy">benzodiazepine</a> class. It is used to treat <a href="/facts/Anxiety/Geekl883">anxiety</a>, <a href="/facts/Insomnia/C1TnQTb2">insomnia</a> and symptoms of <a href="/facts/Drug_withdrawal/lGr6VEBU">withdrawal</a> from <a href="/facts/Alcohol_withdrawal_syndrome/FRX036Vk">alcohol</a>, <a href="/facts/Benzodiazepine_withdrawal_syndrome/5ClvqCLB">benzodiazepines</a>, and other drugs. It is also used to discontinue long term use of other, shorter acting benzodiazepines due to its long half life. 
Chlordiazepoxide has a medium to long <a href="/facts/Half-life/kGVH8BAB">half-life</a>, while its <a href="/facts/Active_metabolite/1zbPKbI0">active metabolite</a> has a very long half-life. The drug has <a href="/facts/Amnesic/PaMeGJH7">amnesic</a>, <a href="/facts/Anticonvulsant/uR8cxJbj">anticonvulsant</a>, <a href="/facts/Anxiolytic/uEWpGca9">anxiolytic</a>, <a href="/facts/Hypnotic/0SBVYkMe">hypnotic</a>, <a href="/facts/Sedative/JWzvq66P">sedative</a>, and <a href="/facts/Skeletal_muscle_relaxant/9jtlSa90">skeletal muscle relaxant</a> properties.
Chlordiazepoxide was patented in 1958 and approved for medical use in 1960. It was the first benzodiazepine to be synthesized and the discovery of chlordiazepoxide was by pure chance. Chlordiazepoxide and other benzodiazepines were initially accepted with widespread public approval, but were followed with widespread public disapproval and recommendations for more restrictive medical guidelines for its use.

Chlordiazepoxide open-in-new

Chlordiazepoxide