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Reference.org
Core-matrix theory of thalamus
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<p>The core-matrix theory of <a href="/facts/Thalamus/UHDtUStc">thalamus</a>, first proposed by <a href="/facts/Edward_G._Jones/Fu1j6Dy9">Ted Jones</a> in 1998, states that neurons in the thalamus belong to either a <a href="/facts/Parvalbumin/1vS6TQQB">parvalbumin</a>-immunopositive core of precisely projecting neurons, or to a <a href="/facts/Calbindin/FeTcatwt">calbindin</a>-immunopositive matrix of diffusely and widely projecting neurons. </p><p>Neurons comprising the core are believed to be involved in propagation of 'driving' information, whereas neurons comprising the matrix are believed to play a more modulatory role.: 1612 The cortical interactions of core neurons maintain content and enable perceptual constancy, whereas through reciprocal interactions with deep-layer cortical neurons, matrix neurons support wakefulness and determine perceptual thresholds.: 1611 </p>