Epigenetic priming

<p>Epigenetic priming (also known as gene priming) is the modification to a cell's <a href="/facts/Epigenome/hjW9Dwgb">epigenome</a> whereby specific <a href="/facts/Chromatin/ha0TJheJ">chromatin domains</a> within a <a href="/facts/Cell_(biology)/bLM9UQvy">cell</a> are <a href="/facts/Chromatin_remodeling/ukC9TjoG">converted</a> from a closed state to an open state, usually as the result of an external biological trigger or <a href="/facts/Signal_transduction/1bs0Me6w">pathway</a>, allowing for <a href="/facts/DNA/nB89Iauz">DNA</a> access by <a href="/facts/Transcription_factor/wro0DPHe">transcription factors</a> or other modification mechanisms. The action of epigenetic priming for a certain region of <a href="/facts/DNA/nB89Iauz">DNA</a> dictates how other <a href="/facts/Regulation_of_gene_expression/9N4G341I">gene regulation mechanisms</a> will be able to act on the DNA later in the cell’s life. Epigenetic priming has been chiefly investigated in <a href="/facts/Neuroscience/o5RV8Cas">neuroscience</a> and <a href="/facts/Cancer_research/w7HvoRug">cancer research</a>, as it has been found to play a key role in <a href="/facts/Memory/zucwQIEX">memory formation</a> within <a href="/facts/Neuron/G7CyTVdH">neurons</a> and <a href="/facts/Tumor_suppressor/Awte4S51">tumor-suppressor gene</a> activation in <a href="/facts/Treatment_of_cancer/dezlwmAe">cancer treatment</a> respectively.
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Epigenetic priming open-in-new

Epigenetic priming