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Vacuum distillation
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<p>Vacuum distillation or distillation under reduced pressure is a type of <a href="/facts/Distillation/plDvUMxn">distillation</a> performed under reduced pressure, which allows the purification of compounds not readily distilled at ambient pressures or simply to save time or energy. This technique separates compounds based on differences in their boiling points. This technique is used when the boiling point of the desired compound is <i>difficult to achieve or will cause the compound to decompose.</i> Reduced pressures decrease the boiling point of compounds. The reduction in boiling point can be calculated using a temperature-pressure <a href="/facts/Nomogram/ysXLNuVY">nomograph</a> using the <a href="/facts/Clausius%E2%80%93Clapeyron_relation/Lo9SfNqM">Clausius–Clapeyron relation</a>. </p>