Signal recognition particle receptor

<p>Signal recognition particle (SRP) receptor, also called the docking protein, is a <a href="/facts/Protein_dimer/c8LwFJPG">dimer</a> composed of 2 different subunits that are associated exclusively with the rough ER in <a href="/facts/Mammal/phSwTzBo">mammalian</a> <a href="/facts/Cell_(biology)/bLM9UQvy">cells</a>. Its main function is to identify the <a href="/facts/Signal_recognition_particle/J9K0m2Mw">SRP</a> units.  SRP (signal recognition particle) is a <a href="/facts/Molecule/N9ljSfFq">molecule</a> that helps the <a href="/facts/Ribosome/CF2u2gtg">ribosome</a>-mRNA-<a href="/facts/Polypeptide/C4ltc7UG">polypeptide</a> complexes to settle down on the <a href="/facts/Biological_membrane/ljBsfK4r">membrane</a> of the <a href="/facts/Endoplasmic_reticulum/DVbLA7GE">endoplasmic reticulum</a>.
</p><p>The eukaryotic SRP receptor (termed SR) is a heterodimer of SR-alpha (70 kDa; SRPRA) and SR-beta (25 kDa; <a href="/facts/SRPRB/UlAnYM8Y">SRPRB</a>), both of which contain a GTP-binding domain, while the prokaryotic SRP receptor comprises only the monomeric loosely membrane-associated SR-alpha homologue FtsY (<a href="https://www.uniprot.org/uniprot/P10121">P10121</a>).
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Signal recognition particle receptor open-in-new

Signal recognition particle receptor