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Sense (molecular biology)
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<p>In <a href="/facts/Molecular_biology/YgqU35ub">molecular biology</a> and <a href="/facts/Genetics/bu8wne0A">genetics</a>, the sense of a <a href="/facts/Nucleic_acid/2tTgcI0v">nucleic acid</a> molecule, particularly of a strand of <a href="/facts/DNA/nB89Iauz">DNA</a> or <a href="/facts/RNA/HxPeNfNj">RNA</a>, refers to the nature of the roles of the strand and its <a href="/facts/Complementarity_(molecular_biology)/WQfqGlBJ">complement</a> in specifying a sequence of <a href="/facts/Amino_acid/WDxYwBny">amino acids</a>. Depending on the context, sense may have slightly different meanings. For example, the negative-sense strand of DNA is equivalent to the template strand, whereas the positive-sense strand is the non-template strand whose nucleotide sequence is equivalent to the sequence of the <a href="/facts/MRNA/oUL6qxQn">mRNA</a> transcript. </p>