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Reference.org
AP-1 transcription factor
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<p>Activator protein 1 (AP-1) is a <a href="/facts/Transcription_factor/wro0DPHe">transcription factor</a> that regulates <a href="/facts/Gene_expression/alCPohLR">gene expression</a> in response to a variety of stimuli, including <a href="/facts/Cytokines/SdWpWABH">cytokines</a>, <a href="/facts/Growth_factor/D1xnRbcH">growth factors</a>, stress, and bacterial and viral infections. AP-1 controls a number of cellular processes including <a href="/facts/Cellular_differentiation/bCVqUG7w">differentiation</a>, <a href="/facts/Cell_growth/wbArMaJU">proliferation</a>, and <a href="/facts/Apoptosis/8dVzSm4y">apoptosis</a>. The structure of AP-1 is a <a href="/facts/Protein_dimer/c8LwFJPG">heterodimer</a> composed of proteins belonging to the <a href="/facts/C-Fos/SHKzGqYX">c-Fos</a>, <a href="/facts/C-Jun/Cbvb15yT">c-Jun</a>, <a href="/facts/Activating_Transcription_Factor/csSC8Q5S">ATF</a> and <a href="/facts/Jun_dimerization_protein/kEqc5r1e">JDP</a> families. </p>