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Reference.org
Integrin alpha-1
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<p>Integrin alpha-1 also CD49a is an <a href="/facts/Integrin/DNYUGbBp">integrin</a> alpha subunit encoded in humans by the gene <i>ITGA1</i>. It makes up half of the α1β1 integrin duplex. Though CD49a can bind a number of ligands including collagen IV, collagen I, and others. </p><p>CD49a has been implicated as a marker of tissue resident memory T cells, where it may be coexpressed with other markers CD103 and CD69. It has been shown to affect the motility of T cells. </p>