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Reference.org
Pierre Robin sequence
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<p>Pierre Robin sequence is a <a href="/facts/Congenital_defect/ESfzQhTx">congenital defect</a> observed in humans which is characterized by <a href="/facts/Craniofacial_abnormality/k91Td2bY">facial abnormalities</a>. The three main features are <a href="/facts/Micrognathia/9sJMTmGD">micrognathia</a> (abnormally small <a href="/facts/Mandible/1ATEfAQa">mandible</a>), which causes <a href="/facts/Glossoptosis/3NVF1xfw">glossoptosis</a> (downwardly displaced or retracted tongue), which in turn causes breathing problems due to obstruction of the <a href="/facts/Respiratory_tract/nnG9UEmr">upper airway</a>. A wide, U-shaped <a href="/facts/Cleft_lip_and_cleft_palate/CoLE8Wbu">cleft palate</a> is commonly also present. PRS is not merely a <a href="/facts/Syndrome/JFVb3x8f">syndrome</a>, but rather it is a <a href="/facts/Sequence_(medicine)/yJ6btln3">sequence</a>—a series of specific developmental malformations which can be attributed to a single cause. </p>