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Tryptase
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<p>Tryptase (<a href="/facts/Enzyme_Commission_number/Y5GNLRKX">EC</a> <a href="https://enzyme.expasy.org/EC/3.4.21.59">3.4.21.59</a>) is the most abundant secretory granule-derived <a href="/facts/Serine_proteinase/kGfEE6hE">serine proteinase</a> contained in <a href="/facts/Mast_cell/szfXss5q">mast cells</a> and has been used as a marker for mast cell activation. <a href="/facts/Club_cell/NoA6TgC5">Club cells</a> contain tryptase, which is believed to be responsible for cleaving the <a href="/facts/Hemagglutinin/1PphF1Ut">hemagglutinin</a> surface protein of <a href="/facts/Influenza_A/bKMeST8Q">influenza A</a> virus, thereby activating it and causing the symptoms of flu. </p>