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Hepatocyte nuclear factor 4
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<p>HNF4 (Hepatocyte Nuclear Factor 4) is a <a href="/facts/Nuclear_receptor/9aYqKxnM">nuclear receptor</a> <a href="/facts/Protein/Jxmagu3E">protein</a> mostly expressed in the <a href="/facts/Liver/Rtp4Fk2b">liver</a>, gut, kidney, and pancreatic <a href="/facts/Beta_cell/MXcTmlDL">beta cells</a> that is critical for liver development. In humans, there are two paralogs of HNF4, <a href="/facts/HNF4A/o5u6pla7">HNF4α</a> and <a href="/facts/HNF4G_(gene)/U7bAjp5D">HNF4γ</a>, encoded by two separate genes <i><a href="https://www.genenames.org/tools/search/#!/genes?query=HNF4A">HNF4A</a></i> and <i><a href="https://www.genenames.org/tools/search/#!/genes?query=HNF4G">HNF4G</a></i> respectively. </p>