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Reference.org
Selective estrogen receptor modulator
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<p>Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs), are a class of <a href="/facts/Drug/FFFUI9n4">drugs</a> that act on <a href="/facts/Estrogen_receptor/dEGaNney">estrogen receptors</a> (ERs). Compared to pure ER <a href="/facts/Agonist/nz8U5NNp">agonists</a>–<a href="/facts/Receptor_antagonist/PuXHVNdV">antagonists</a> (e.g., <a href="/facts/Full_agonist/nz8U5NNp">full agonists</a> and <a href="/facts/Silent_antagonist/PuXHVNdV">silent antagonists</a>), SERMs are more tissue-specific, allowing them to selectively inhibit or stimulate <a href="/facts/Estrogen/dPEewnDV">estrogen</a>-like action in various tissues. </p>