Technetium (99mTc) sestamibi

<p>Technetium (99mTc) sestamibi (<a href="/facts/International_Nonproprietary_Name/wYL655x6">INN</a>) (commonly sestamibi; <a href="/facts/United_States_Pharmacopeia/CyYDYG8m">USP</a>: technetium Tc 99m sestamibi; trade name Cardiolite) is a pharmaceutical agent used in <a href="/facts/Nuclear_medicine/L9Dzjd90">nuclear medicine</a> imaging. The drug is a <a href="/facts/Coordination_complex/1tCyeQUm">coordination complex</a> consisting of the <a href="/facts/Radioisotope/5WpCfbdq">radioisotope</a> <a href="/facts/Technetium-99m/HgIqtvrv">technetium-99m</a> bound to six (sesta=6) methoxyisobutylisonitrile (MIBI) <a href="/facts/Ligand/6etB3qeW">ligands</a>.  The anion is not defined. The <a href="/facts/Generic_drug/IF6AXDVX">generic drug</a> became available late September 2008. A scan of a patient using MIBI is commonly known as a "MIBI scan".
</p><p>Sestamibi is taken up by tissues with large numbers of <a href="/facts/Mitochondria/ErHqrdJ1">mitochondria</a> and negative plasma membrane potentials. Sestamibi is mainly used to image the <a href="/facts/Myocardium/oMqU4Sdu">myocardium</a> (heart muscle). It is also used in the work-up of primary <a href="/facts/Hyperparathyroidism/WnCEnPUP">hyperparathyroidism</a> to identify <a href="/facts/Parathyroid/HmyY4S4m">parathyroid</a> adenomas, for radioguided surgery of the parathyroid and in the work-up of possible <a href="/facts/Breast_cancer/6hME580v">breast cancer</a>.
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Technetium (99mTc) sestamibi open-in-new

Technetium (99mTc) sestamibi