"Make Room for Lisa" is the sixteenth episode of the tenth season of the American animated television series The Simpsons. It first aired on Fox in the United States on February 28, 1999. The main plot has Homer and Lisa embark on a spiritual journey via a sensory deprivation tank.
"Make Room for Lisa" was written by Brian Scully and was the first full The Simpsons episode Matthew Nastuk directed, having received a co-director credit for "D'oh-in' in the Wind", for which he directed one scene. The subplot, which involves Marge eavesdropping on phone calls using a baby monitor, was inspired by former showrunners Bill Oakley and Josh Weinstein, who also listened to private phone calls with a monitor. The episode contains references to the American sitcom All in the Family, and advises children to be accepting of their parents.
In its original broadcast, the episode was seen by approximately 7.6 million viewers, finishing in 52nd place in the ratings the week it aired.
Following the home video release of The Simpsons - The Complete Tenth Season, "Make Room for Lisa" received mixed reviews from critics.