Sebaceous hyperplasia

Sebaceous hyperplasia is a disorder of the <a href="/facts/Sebaceous_gland/HKMXmv1Y">sebaceous glands</a> in which they become enlarged, producing flesh-colored or yellowish, shiny, often umbilicated bumps. Sebaceous hyperplasia, primarily affecting older patients in high-concentration areas like the face, head, and neck, typically has a 2-4 mm diameter and causes no symptoms. The lesions are often surrounded by <a href="/facts/Telangiectasia/72MBl6oP">telangiectatic</a> <a href="/facts/Blood_vessel/FG3GjPNW">blood vessels</a>, also known as "crown vessels," and a central dell, which is in line with the origin of the lesions.
<a href="/facts/Sebaceous_gland/HKMXmv1Y">Sebaceous glands</a> are glands located within the <a href="/facts/Skin/4havlLzG">skin</a> and are responsible for secreting an oily substance named <a href="/facts/Sebum/HKMXmv1Y">sebum</a>. They are commonly associated with <a href="/facts/Hair_follicle/SXsAKufM">hair follicles</a> but they can be found in hairless regions of the skin as well. Their secretion lubricates the skin, protecting it from drying out or becoming irritated.
Murine studies suggest topical irritants and <a href="/facts/Carcinogen/soH8Y9CE">carcinogens</a> may contribute to sebaceous hyperplasia development, with <a href="/facts/Immunosuppression/22GHUHkr">immunosuppression</a> with <a href="/facts/Cyclosporin_A/tcIToHvK">cyclosporin A</a> or <a href="/facts/HIV/ulY2rgzu">HIV</a> infection increasing the likelihood.
Sebaceous hyperplasia is a condition that can be diagnosed clinically but requires a <a href="/facts/Biopsy/A0TdRRlr">biopsy</a> for confirmation. It shares similarities with folliculosebaceous unit architecture but has larger and expanded <a href="/facts/Sebaceous_gland/HKMXmv1Y">sebaceous glands</a>. Identifying sebaceous hyperplasia using <a href="/facts/Dermatoscopy/se2HbBkB">dermatoscopy</a> can help identify it from other lesions. The dermoscopic characteristics include "crown vessels" clusters of white or yellow <a href="/facts/Nodule_(medicine)/BgCs3GNE">nodules</a>, a distinct asymmetrical milky-white structure called the cumulus sign, and a central umbilication called the "bonbon toffee sign."
Sebaceous hyperplasia treatment involves various techniques like <a href="/facts/Cryotherapy/gCfk5RAT">cryotherapy</a>, <a href="/facts/Dichloroacetic_acid/dtro1JSN">bichloroacetic acid</a>, shave excision, <a href="/facts/Carbon-dioxide_laser/RcnclQbA">carbon dioxide laser</a> ablation, <a href="/facts/Electrodesiccation_and_curettage/TRGmMEBD">electrodessication</a>, erbium/yttrium aluminum garnet laser ablation, and <a href="/facts/Pulsed_dye_laser/IRw09pbC">pulsed-dye laser</a> photothermolysis.

Sebaceous hyperplasia open-in-new

Sebaceous hyperplasia