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Reference.org
WW domain
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<p>The WW domain (also known as the rsp5-domain or WWP repeating <a href="/facts/Structural_motif/g8EBDBGW">motif</a>) is a modular <a href="/facts/Protein_domain/oUpFcSsl">protein domain</a> that mediates specific interactions with protein ligands. This domain is found in a number of unrelated signaling and structural proteins and may be repeated up to four times in some proteins. Apart from binding preferentially to proteins that are <a href="/facts/Proline/x1ABSW5A">proline</a>-rich, with particular proline-motifs, [AP]-P-P-[AP]-Y, some WW domains bind to <a href="/facts/Phosphoserine/nWq6mt9E">phosphoserine</a>- and <a href="/facts/Phosphothreonine/7zffFQ6W">phosphothreonine</a>-containing motifs. </p>