Phospho-N-acetylmuramoyl-pentapeptide-transferase

In <a href="/facts/Enzymology/DSI1Fh7y">enzymology</a>, a phospho-N-acetylmuramoyl-pentapeptide-transferase (<a href="/facts/Enzyme_Commission_number/Y5GNLRKX">EC</a> <a href="https://enzyme.expasy.org/EC/2.7.8.13">2.7.8.13</a>) is an <a href="/facts/Enzyme/DSI1Fh7y">enzyme</a> that <a href="/facts/Catalysis/LPBS7TQC">catalyzes</a> the <a href="/facts/Chemical_reaction/GpqWlKrz">chemical reaction</a>

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate 
 
 
 
 ⇌
 
 
 {\displaystyle \rightleftharpoons }
 
 UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
Thus, the two <a href="/facts/Substrate_(biochemistry)/6MnaV19h">substrates</a> of this enzyme are UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) and <a href="/facts/Undecaprenyl_phosphate/3QbNd63j">undecaprenyl phosphate</a>, whereas its 2 <a href="/facts/Product_(chemistry)/8uCoDUdv">products</a> are <a href="/facts/Uridine_monophosphate/TkB63ofX">UMP</a> and Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.
This enzyme participates in <a href="/facts/Peptidoglycan_biosynthesis/lflRRUNw">peptidoglycan biosynthesis</a>. It can be expressed efficiently by a <a href="/facts/Cell-free_system/Tow6j88h">cell-free</a> protein expression system.

Phospho-N-acetylmuramoyl-pentapeptide-transferase open-in-new

Phospho-N-acetylmuramoyl-pentapeptide-transferase