3,5-Dimethylpyrazole

3,5-Dimethylpyrazole is an <a href="/facts/Organic_compound/gqCNaN45">organic compound</a> with the formula (CH3C)2CHN2H. It is one of several isomeric derivatives of <a href="/facts/Pyrazole/mNToRYlQ">pyrazole</a> that contain two methyl substituents. The compound is unsymmetrical but the corresponding conjugate acid (pyrazolium) and conjugate base (pyrazolide) have C2v symmetry. It is a white solid that dissolves well in polar organic solvents.
It is a precursor to a variety of ligands that are widely studied in <a href="/facts/Coordination_chemistry/1tCyeQUm">coordination chemistry</a> including <a href="/facts/Trispyrazolylborate/CYfYo0f6">trispyrazolylborate</a>, a trispyrazolylmethane, and a pyrazolyldiphosphine. 
Condensation of <a href="/facts/Acetylacetone/Ku1k97xz">acetylacetone</a> and <a href="/facts/Hydrazine/G7P5ITzU">hydrazine</a> gives 3,5-dimethylpyrazole:

CH3C(O)CH2C(O)CH3   +   N2H4   →   (CH3C)2CHN2H   +   2 H2O
It has found use as a blocking agent for isocyanates.

3,5-Dimethylpyrazole open-in-new

3,5-Dimethylpyrazole