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Tyrocidine
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<p>Tyrocidine is a mixture of cyclic decapeptides produced by the bacteria <i><a href="/facts/Brevibacillus_brevis/AlqT54UT">Brevibacillus brevis</a></i> found in soil. It can be composed of 4 different amino acid sequences, giving tyrocidine A–D (See figure 1). Tyrocidine is the major constituent of <a href="/facts/Tyrothricin/jcGUBQXB">tyrothricin</a>, which also contains <a href="/facts/Gramicidin/lmnnzc9g">gramicidin</a>. Tyrocidine was the first commercially available antibiotic, but has been found to be toxic toward human blood and reproductive cells. The function of tyrocidine within its host <i>B. brevis</i> is thought to be regulation of <a href="/facts/Sporulation/6qDRdcrs">sporulation</a>. </p> <p>Tyrocidines A, B, and C are cyclic decapeptides. The biosynthesis of tyrocidine involves three enzymes. Parts of its sequence are identical to <a href="/facts/Gramicidin/lmnnzc9g">gramicidin</a> S. </p>