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GRADE approach
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<p>The GRADE approach (Grading of Recommendations Assessment, Development and Evaluation) is a method of assessing the certainty in evidence (also known as quality of evidence or confidence in effect estimates) and the strength of recommendations in <a href="/facts/Health_care/LPS1WKbI">health care</a>. It provides a structured and transparent evaluation of the importance of outcomes of alternative management strategies, acknowledgment of <a href="/facts/Patient/b0SWyyVD">patients</a> and the public values and preferences, and comprehensive criteria for downgrading and upgrading certainty in evidence. It has important implications for those summarizing evidence for <a href="/facts/Systematic_review/dGvq3BGx">systematic reviews</a>, health technology assessments, and <a href="/facts/Medical_guideline/l4EfFfa2">clinical practice guidelines</a> as well as other decision makers. </p>