Indo-Pakistani Sign Language (IPSL) is the predominant sign language in the subcontinent of South Asia, used by at least 15 million deaf signers. As with many sign languages, it is difficult to estimate numbers with any certainty, as the Census of India does not list sign languages and most studies have focused on the north and urban areas. As of 2024, it is the most used sign language in the world, and Ethnologue ranks it as the 149th most "spoken" language in the world.
Some scholars regard varieties in India, Pakistan, Bangladesh and possibly Nepal as variety of Indo-Pakistani Sign Language. Others recognize some varieties as separate languages. The ISO standard currently distinguishes: