Clos may refer to:
People
Other uses
- CLOS, Command line-of-sight, a method of guiding a missile to its intended target
- Clos network, a kind of multistage switching network
- Clos (vineyard), a walled vineyard; used in France, Germany and California
- an alternative spelling of close in the name of a Cul-de-sac
- Common Lisp Object System (CLOS)