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Linoleate isomerase

Enzyme

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In enzymology, a linoleate isomerase (EC 5.2.1.5) is an enzyme that catalyzes the chemical reaction

9-cis,12-cis-octadecadienoate ⇌ {\displaystyle \rightleftharpoons } 9-cis,11-trans-octadecadienoate

Hence, this enzyme has one substrate, 9-cis,12-cis-octadecadienoate, and one product, 9-cis,11-trans-octadecadienoate.

This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is linoleate Delta12-cis-Delta11-trans-isomerase. This enzyme is also called linoleic acid isomerase. This enzyme participates in linoleic acid metabolism.

Kepler CR, Tove SB (1967). "Biohydrogenation of unsaturated fatty acids. 3. Purification and properties of a linoleate delta-12-cis, delta-11-trans-isomerase from Butyrivibrio fibrisolvens". J. Biol. Chem. 242 (24): 5686–92. PMID 5633396.