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Presqualene diphosphate synthase
Class of enzymes

Presqualene diphosphate synthase (EC 2.5.1.103, SSL-1 (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming). This enzyme catalyses the following chemical reaction

2 (2E,6E)-farnesyl diphosphate ⇌ {\displaystyle \rightleftharpoons } presqualene diphosphate + diphosphate

This enzyme is isolated from the green alga Botryococcus braunii BOT22.

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References

  1. Niehaus TD, Okada S, Devarenne TP, Watt DS, Sviripa V, Chappell J (2011). "Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii". Proc. Natl. Acad. Sci. USA. 108 (30): 12260–12265. Bibcode:2011PNAS..10812260N. doi:10.1073/pnas.1106222108. PMC 3145686. PMID 21746901. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145686