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RGS3
Protein-coding gene in the species Homo sapiens

Regulator of G-protein signaling 3 is a protein that in humans is encoded by the RGS3 gene.

This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.

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Further reading

References

  1. Druey KM, Blumer KJ, Kang VH, Kehrl JH (May 1996). "Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family". Nature. 379 (6567): 742–6. Bibcode:1996Natur.379..742D. doi:10.1038/379742a0. PMID 8602223. S2CID 4362632. https://zenodo.org/record/1233178

  2. Linares JL, Wendling C, Tomasetto C, Rio MC (Nov 2000). "C2PA, a new protein expressed during mouse spermatogenesis". FEBS Lett. 480 (2–3): 249–54. doi:10.1016/S0014-5793(00)01942-6. PMID 11034339. S2CID 12703563. /wiki/Doi_(identifier)

  3. "Entrez Gene: RGS3 regulator of G-protein signalling 3". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5998

  4. "Entrez Gene: RGS3 regulator of G-protein signalling 3". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5998