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Thymol blue
Chemical compound

Thymol blue (thymolsulfonephthalein) is a brownish-green or reddish-brown crystalline powder that is used as a pH indicator. It is insoluble in water but soluble in alcohol and dilute alkali solutions.

It transitions from red to yellow at pH 1.2–2.8 and from yellow to blue at pH 8.0–9.6. It is usually a component of Universal indicator.

At wavelength (378 - 382) nm, extinction coefficient > 8000 and at wavelength (298 - 302) nm, the extinction coefficient > 12000.

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Structures

Thymol blue has different structures at different pH.

thymol blue.

Safety

It may cause irritation. Its toxicological properties have not been fully investigated.2 Harmful if swallowed, Acute Toxicity. Only Hazardous when percent values are above 10%.3

Bibliography

  • Merck. "Thymol Blue." The Merck Index. 14th ed. 2006. Accessed via web on 2007-02-25.
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References

  1. "Product Specification: Thymol Blue- ACS reagent" (PDF). Sigma-Aldrich. 9 October 2017. p. 1. http://www.sigmaaldrich.com/Graphics/COfAInfo/SigmaSAPQM/SPEC/11/114545/114545-BULK_______SIAL_____.pdf

  2. "Thymol Blue MSDS". Fisher Scientific. Retrieved 2024-07-23. https://fscimage.fishersci.com/msds/60620.htm#:~:text=Eye:%20May%20cause%20eye%20irritation,irritation%20of%20the%20digestive%20tract.

  3. "Thymol blue". PubChem. Retrieved 2017-10-09. https://pubchem.ncbi.nlm.nih.gov/compound/Thymol_blue#section=GHS-Classification