Treponematosis is a term used to individually describe any of the diseases caused by four members of the bacterial genus Treponema. The four diseases are collectively referred to as treponematoses:
- Syphilis (Treponema pallidum pallidum)
- Yaws (Treponema pallidum pertenue)
- Bejel (Treponema pallidum endemicum)
- Pinta (Treponema carateum)
Traditional laboratory tests cannot distinguish the treponematoses. However, sequence differences among the T. pallidum subspecies have been identified. Molecular approaches involving PCR to identify these sequences are being developed.
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References
Giacani, L.; Lukehart, S. A. (2014). "The Endemic Treponematoses". Clinical Microbiology Reviews. 27 (1): 89–115. doi:10.1128/CMR.00070-13. PMC 3910905. PMID 24396138. /wiki/Sheila_Lukehart ↩
Marks M, Solomon AW, Mabey DC (October 2014). "Endemic treponemal diseases". Transactions of the Royal Society of Tropical Medicine and Hygiene. 108 (10): 601–7. doi:10.1093/trstmh/tru128. PMC 4162659. PMID 25157125. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162659 ↩
Mitjà O, Šmajs D, Bassat Q (2013). "Advances in the diagnosis of endemic treponematoses: yaws, bejel, and pinta". PLOS Neglected Tropical Diseases. 7 (10): e2283. doi:10.1371/journal.pntd.0002283. PMC 3812090. PMID 24205410. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812090 ↩