In English there are three primary privative prefixes, all cognate from Proto-Indo-European:
These all stem from a PIE syllabic nasal privative *n̥-, the zero ablaut grade of the negation *ne, i.e. "n" used as a vowel, as in some English pronunciations of "button". This is the source of the 'n' in 'an-' privative prefixed nouns deriving from the Greek, which had both. For this reason, it appears as an- before vowel, e.g. anorexia, anesthesia.
The same prefix appears in Sanskrit, also as a- अ-, an- अन्- ( , -n- infix). In Slavic languages the privative is nie- and u-, e.g. nieboga, ubogi. In North Germanic languages, the -n- has disappeared and Old Norse has ú- (e.g. ú-dáins-akr), which became u- in Danish and Norwegian, o- in Swedish, and ó- in Icelandic.
Privative prefixes are not feature of Indo-European languages only, but also exist in languages belonging to other families, such as Hebrew: אל־, romanized: al- (Semitic).
Many words introduced into the English from the Latin start with the prefix in-. While often, it is a privative, it is not always so. Even if it is a privative, the meaning may be unclear to those who are not familiar with the word.2 The following three examples illustrate that:
The prefix in- arises from the Latin for "in, inside, within" and inflammable derives from the Latin root inflammāre6 meaning "able to be set alight, able to kindle a flame". Since at least the 1920s, there have been calls to stop using inflammable and substitute it exclusively with flammable to avoid the confusion that occurs even by native English-speakers.7
Some languages have privative suffixes; -less is an example in English. Further examples are -t(a)lan or -t(e)len in Hungarian or -ton/-tön in Finnish (non-IE languages).
"privare". William Whitaker's Words. Archived from the original on 2012-04-14. https://web.archive.org/web/20120414202617/http://lysy2.archives.nd.edu/cgi-bin/words.exe?privare ↩
"You're 'in-' for some confusion with prefixes". Michigan Radio. 2014-03-02. Retrieved 2017-03-12. http://michiganradio.org/post/you-re-some-confusion-prefixes ↩
The meaning "able to be given a value" is largely obsolete today. ↩
"Invaluable | Define Invaluable at Dictionary.com". Dictionary.reference.com. Retrieved 2017-03-12. http://dictionary.reference.com/browse/invaluable?s=t ↩
Nordquist, Richard. "Confusables: Flammable, Inflammable, and Nonflammable". Grammar.about.com. Retrieved 2017-03-12. http://grammar.about.com/od/alightersideofwriting/a/Flammable-Inflammable-And-Nonflammable.htm ↩
"Inflamed | Define Inflamed at Dictionary.com". Dictionary.reference.com. Retrieved 2017-03-12. http://dictionary.reference.com/browse/inflamed?s=t ↩