Protein structure database

<h2 id="the-protein-data-bank">The Protein Data Bank</h2>
<p class="note">Main article: <a href="/facts/Protein_Data_Bank/oUhq4ABD">Protein Data Bank</a></p>
<p>The Protein Data Bank (PDB) was established in 1971 as the central <a href="/facts/Archive/BgCG3dxa">archive</a> of all experimentally determined protein structure data. Today the PDB is maintained by an international consortia collectively known as the <a href="/facts/Worldwide_Protein_Data_Bank/aTP4kMfK">Worldwide Protein Data Bank</a> (wwPDB). The mission of the wwPDB is to maintain a single archive of <a href="/facts/Macromolecular/039ULSLg">macromolecular</a> structural data that is freely and publicly available to the global community.<a class="footnote-ref" id="fnref:2" href="#fn:2"><sup>2</sup></a><a class="footnote-ref" id="fnref:3" href="#fn:3"><sup>3</sup></a>
</p>
<h2 id="list-of-other-protein-structure-databases">List of other protein structure databases</h2>
<p>Because the PDB releases data into the <a href="/facts/Public_domain/YWKMDKw4">public domain</a>, the data has been used in various other protein structure databases.
</p><p>Examples of protein structure databases include (in alphabetical order);
</p>
<a href="http://www.molmovdb.org">Database of Macromolecular Movements</a>
describes the motions that occur in proteins and other macromolecules, particularly using movies
<a href="http://www.dynameomics.org">Dynameomics</a>
a data warehouse of molecular dynamics simulations and analyses of proteins representing all known protein fold families
<a href="http://jenalib.fli-leibniz.de/">JenaLib</a>
the Jena Library of Biological Macromolecules is aimed at a better dissemination of information on three-dimensional biopolymer structures with an emphasis on visualization and analysis.
<a href="/facts/ModBase/MWxQDNh3">ModBase</a>
a database of three-dimensional protein models calculated by comparative modeling
<a href="http://oca.weizmann.ac.il/oca-bin/ocamain">OCA</a>
a browser-database for protein structure/function - The OCA integrates information from <a href="/facts/KEGG/pK5La8ad">KEGG</a>, <a href="/facts/OMIM/PkW3zCCU">OMIM</a>, PDBselect, <a href="/facts/Pfam/BKJa293w">Pfam</a>, <a href="/facts/PubMed/JlHAvMHt">PubMed</a>, <a href="/facts/Structural_Classification_of_Proteins/4uz6VcF7">SCOP</a>, <a href="/facts/SwissProt/lfDDHjAl">SwissProt</a>, and others.
<a href="/facts/Orientations_of_Proteins_in_Membranes_database/R1bTDgkq">OPM</a>
provides spatial positions of protein three-dimensional structures with respect to the <a href="/facts/Lipid_bilayer/CQKQ9l3g">lipid bilayer</a>.
<a href="http://ispc.weizmann.ac.il/oca-docs/lite-why.html">PDB Lite</a>
derived from OCA, PDB Lite was provided to make it as easy as possible to find and view a macromolecule within the PDB
<a href="http://www.ebi.ac.uk/pdbsum/">PDBsum</a>
provides an overview macromolecular structures in the PDB, giving schematic diagrams of the molecules in each structure and of the interactions between them
<a href="https://web.archive.org/web/20131225065028/http://pdbtm.enzim.hu/">PDBTM</a>
the Protein Data Bank of <a href="/facts/Membrane_protein/FboTeM8Q">Transmembrane Proteins</a> — a selection of the PDB.
<a href="/facts/PDBWiki/7Uogrgo2">PDBWiki</a>
a community annotated knowledge base of biological molecular structures <a href="http://pdbwiki.org">[1]</a>
<a href="/facts/ProtCID/BvHsdD1S">ProtCID</a>
The Protein Common Interface Database (<a href="http://dunbrack2.fccc.edu/protcid">ProtCID</a>) is a database of similar protein–protein interfaces in crystal structures of homologous proteins.
<a href="https://www.ncbi.nlm.nih.gov/protein">Protein</a>
the <a href="/facts/National_Institute_of_Health/G3Eytfcc">NIH</a> protein database, a collection of sequences from several sources, including translations from annotated coding regions in <a href="/facts/GenBank/XyMcrktE">GenBank</a>, <a href="/facts/RefSeq/5kBXXR8s">RefSeq</a> and Third Party Annotation, as well as records from <a href="/facts/SwissProt/lfDDHjAl">SwissProt</a>, <a href="/facts/Protein_Information_Resource/wHD5WbCB">PIR</a>, PRF, and <a href="/facts/Protein_Data_Bank/oUhq4ABD">PDB</a>
<a href="/facts/Proteopedia/C2LhX6kn">Proteopedia</a>
the collaborative, 3D encyclopedia of proteins and other molecules. A wiki that contains a page for every entry in the PDB (>100,000 pages), with a <a href="/facts/Jmol/Ek2m784k">Jmol</a> view that highlights functional sites and ligands. Offers an easy-to-use scene-authoring tool so you don't have to learn Jmol script language to create customized molecular scenes. Custom scenes are easily attached to "green links" in descriptive text that display those scenes in Jmol.
<a href="http://www.proteinlounge.com">ProteinLounge</a>
a protein databases that includes visuals of protein structure.  Also, includes protein pathways and gene sequences including other tools.
<a href="/facts/Structural_Classification_of_Proteins/4uz6VcF7">SCOP</a>
the Structural Classification of Proteins <a href="https://web.archive.org/web/20070911012207/http://scop.mrc-lmb.cam.ac.uk/scop/">[2]</a> a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known.
<a href="http://swissmodel.expasy.org/repository/">SWISS-MODEL Repository</a>
a database of annotated protein models calculated by homology modeling
<a href="/facts/TOPSAN/GNpFgTCD">TOPSAN</a>
the Open Protein Structure Annotation Network — a wiki designed to collect, share and distribute information about protein three-dimensional structures.

<h2 id="references">References</h2>

<ol>
<li id="fn:1"><p>Laskowski, RA (2011). "Protein structure databases". Mol Biotechnol. 48 (2): 183–98. doi:10.1007/s12033-010-9372-4. PMID 21225378. S2CID 45184564. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li>
<li id="fn:2"><p>Berman, H. M. (January 2008). "The Protein Data Bank: a historical perspective" (PDF). Acta Crystallographica Section A. A64 (1): 88–95. doi:10.1107/S0108767307035623. PMID 18156675. <a href="http://journals.iucr.org/a/issues/2008/01/00/sc5004/sc5004.pdf" target="_blank">http://journals.iucr.org/a/issues/2008/01/00/sc5004/sc5004.pdf</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li>
<li id="fn:3"><p>Laskowski RA, Hutchinson EG, Michie AD, Wallace AC, Jones ML, Thornton JM (December 1997). "PDBsum: a Web-based database of summaries and analyses of all PDB structures". Trends Biochem. Sci. 22 (12): 488–90. doi:10.1016/S0968-0004(97)01140-7. PMID 9433130. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li>
</ol>

Protein structure database open-in-new

Protein structure database