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Hoarse voice
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<h2 id="types">Types</h2> <p>Voice disorders can be divided into two broad categories: organic and functional.<a class="footnote-ref" id="fnref:18" href="#fn:18"><sup>18</sup></a> The distinction between these broad classes stems from their cause, whereby organic dysphonia results from some sort of physiological change in one of the subsystems of speech (for voice, usually respiration, laryngeal anatomy, and/or other parts of the vocal tract are affected). Conversely, functional dysphonia refers to hoarseness resulting from vocal use (i.e. overuse/abuse).<a class="footnote-ref" id="fnref:19" href="#fn:19"><sup>19</sup></a> Furthermore, according to <a href="/facts/American_Speech%E2%80%93Language%E2%80%93Hearing_Association/QgLcyC0n">ASHA</a>, organic dysphonia can be subdivided into structural and neurogenic; neurogenic dysphonia is defined as impaired functioning of the vocal structure due to a neurological problem (in the <a href="/facts/Central_nervous_system/k8I6To97">central nervous system</a> or <a href="/facts/Peripheral_nervous_system/KjVpVnHU">peripheral nervous system</a>); in contrast, structural dysphonia is defined as impaired functioning of the vocal mechanism that is caused by some sort of physical change (e.g. a lesion on the vocal folds).<a class="footnote-ref" id="fnref:20" href="#fn:20"><sup>20</sup></a> Notably, an additional subcategory of functional dysphonia recognized by professionals is psychogenic dysphonia, which can be defined as a type of voice disorder that has no known cause and can be presumed to be a product of some sort of psychological stressors in one's environment.<a class="footnote-ref" id="fnref:21" href="#fn:21"><sup>21</sup></a><a class="footnote-ref" id="fnref:22" href="#fn:22"><sup>22</sup></a> It is important to note that these types are not mutually exclusive and much overlap occurs. For example, <a href="/facts/Muscle_Tension_Dysphonia/RytgCpVL">Muscle Tension Dysphonia</a> (MTD) has been found to be a result of many different causes including the following: MTD in the presence of an organic pathology (i.e. organic type), MTD stemming from vocal use (i.e. functional type), and MTD as a result of personality and/or psychological factors (i.e. psychogenic type).<a class="footnote-ref" id="fnref:23" href="#fn:23"><sup>23</sup></a><a class="footnote-ref" id="fnref:24" href="#fn:24"><sup>24</sup></a> </p> <ul><li>Organic dysphonia <ul><li>Laryngitis (Acute: viral, bacterial) - (Chronic: smoking, <a href="/facts/Gastroesophageal_reflux_disease/8YhncnDz">GERD</a>, <a href="/facts/Laryngopharyngeal_reflux/z1gy3yVu">LPR</a>)</li> <li>Neoplasm (Premalignant: dysplasia) - (Malignant: Squamous cell carcinoma)</li> <li>Trauma (Iatrogenic: surgery, intubation) - (Accidental: blunt, penetrating, thermal)</li> <li>Endocrine (Hypothyroidism, hypogonadism)</li> <li>Haematological (Amyloidosis)</li> <li>Iatrogenic (inhaled corticosteroids)</li></ul></li> <li>Functional dysphonia <ul><li>Psychogenic</li> <li>Vocal misuse</li> <li>Idiopathic</li></ul></li></ul> <h2 id="causes">Causes</h2> <p>The most common causes of hoarseness is <a href="/facts/Laryngitis/N0KTAoV1">laryngitis</a> (acute 42.1%; chronic 9.7%) and functional dysphonia (30%).<a class="footnote-ref" id="fnref:25" href="#fn:25"><sup>25</sup></a> Hoarseness can also be caused by laryngeal <a href="/facts/Tumours/K0ytzmPz">tumours</a> (benign 10.7 - 31%; malignant 2.2 - 3.0%).<a class="footnote-ref" id="fnref:26" href="#fn:26"><sup>26</sup></a> Causes that are overall less common include <a href="/facts/Neurogenic/CDxRKU2U">neurogenic</a> conditions (2.8 - 8.0%), psychogenic conditions (2.0 - 2.2%), and aging (2%).<a class="footnote-ref" id="fnref:27" href="#fn:27"><sup>27</sup></a> </p><p>A variety of different causes, which result in abnormal vibrations of the vocal folds, can cause dysphonia. These causes can range from vocal abuse and misuse to <a href="/facts/Systemic_disease/KekpoXyr">systemic diseases</a>. Causes of dysphonia can be divided into five basic categories, although overlap may occur between categories.<a class="footnote-ref" id="fnref:28" href="#fn:28"><sup>28</sup></a><a class="footnote-ref" id="fnref:29" href="#fn:29"><sup>29</sup></a><a class="footnote-ref" id="fnref:30" href="#fn:30"><sup>30</sup></a><a class="footnote-ref" id="fnref:31" href="#fn:31"><sup>31</sup></a> (Note that this list is not exhaustive): </p> <ol><li><a href="/facts/Neoplasm/K0ytzmPz">Neoplastic</a>/structural: Abnormal growths of the vocal fold tissue. <ul><li><a href="/facts/Dysplasia/sR1UKrbB">Dysplasia</a></li> <li><a href="/facts/Cyst/N1n2ogU9">Cysts</a></li> <li>Polyps</li> <li><a href="/facts/Vocal_fold_nodule/wNnXc38A">Nodules</a></li> <li><a href="/facts/Carcinoma/NE9UY4VB">Carcinoma</a></li></ul></li> <li><a href="/facts/Inflammation/Ura86MIy">Inflammatory</a>: Changes in the vocal fold tissue as a result of inflammation. <ul><li><a href="/facts/Allergy/dYAVosh8">Allergy</a></li> <li><a href="/facts/Infection/182XrncP">Infections</a></li> <li><a href="/facts/Gastroesophageal_reflux_disease/8YhncnDz">Reflux</a></li> <li>Smoking</li> <li>Trauma</li> <li>Voice abuse</li></ul></li> <li>Neuromuscular: Disturbances in any of the components of the <a href="/facts/Nervous_system/CDxRKU2U">nervous system</a> that control laryngeal function. <ul><li><a href="/facts/Multiple_sclerosis/vghXl0IQ">Multiple Sclerosis</a></li> <li><a href="/facts/Myasthenia_gravis/9kKmyBln">Myasthenia Gravis</a></li> <li><a href="/facts/Parkinson%27s_disease/xpekKj6x">Parkinson's disease</a></li> <li><a href="/facts/Spasmodic_dysphonia/4hzAR9AM">Spasmodic Dysphonia</a></li> <li><a href="/facts/Nerve_injury/1dnoUBzk">Nerve injury</a></li></ul></li> <li>Associated Systemic Diseases: <a href="/facts/Systemic_disease/KekpoXyr">Systemic diseases</a> which have manifestations that affect the voice. <ul><li><a href="/facts/Acromegaly/caqcbMmM">Acromegaly</a></li> <li><a href="/facts/Amyloidosis/FeuTXVdn">Amyloidosis</a></li> <li><a href="/facts/Hypothyroidism/oqtQDu2F">Hypothyroidism</a></li> <li><a href="/facts/Sarcoidosis/qgV7Uoe8">Sarcoidosis</a></li></ul></li> <li>Technical: Associated with poor muscle functioning or psychological stresses, with no corresponding physiological abnormalities of the larynx. <ul><li>Psychogenic such as dissociation disorder<a class="footnote-ref" id="fnref:32" href="#fn:32"><sup>32</sup></a></li> <li>Excess demands</li> <li>Stress</li> <li>Vocal strain</li></ul></li></ol> <h3>Employment</h3> <p>It has been suggested that certain occupational groups may be at increased risk of developing dysphonia<a class="footnote-ref" id="fnref:33" href="#fn:33"><sup>33</sup></a><a class="footnote-ref" id="fnref:34" href="#fn:34"><sup>34</sup></a> due to the excessive or intense vocal demands of their work.<a class="footnote-ref" id="fnref:35" href="#fn:35"><sup>35</sup></a> Research on this topic has primarily focused on teachers and singers, although some studies have examined other groups of heavy voice users (e.g. actors, cheerleaders, aerobic instructors, etc.).<a class="footnote-ref" id="fnref:36" href="#fn:36"><sup>36</sup></a><a class="footnote-ref" id="fnref:37" href="#fn:37"><sup>37</sup></a> At present, it is known that teachers and singers are likely to report dysphonia.<a class="footnote-ref" id="fnref:38" href="#fn:38"><sup>38</sup></a><a class="footnote-ref" id="fnref:39" href="#fn:39"><sup>39</sup></a> Moreover, physical education teachers, teachers in noisy environments, and those who habitually use a loud speaking voice are at increased risk.<a class="footnote-ref" id="fnref:40" href="#fn:40"><sup>40</sup></a> The term <a href="/facts/Pharyngitis/PF8tKu39">clergyman's throat</a> or <i>dysphonia clericorum</i> was previously used for painful dysphonia associated with public speaking, particularly among preachers.<a class="footnote-ref" id="fnref:41" href="#fn:41"><sup>41</sup></a> However, the exact prevalence rates for occupational voice users are unclear, as individual studies have varied widely in the methodologies used to obtain data (e.g. employing different <a href="/facts/Operational_definition/CDnIenDo">operational definitions</a> for "singer").<a class="footnote-ref" id="fnref:42" href="#fn:42"><sup>42</sup></a><a class="footnote-ref" id="fnref:43" href="#fn:43"><sup>43</sup></a> </p> <h2 id="mechanism">Mechanism</h2> <p>Located in the anterior portion of the neck is the <a href="/facts/Larynx/0bhtXI3Q">larynx</a> (also known as the voice box), a structure made up of several supporting cartilages and ligaments, which houses the <a href="/facts/Vocal_folds/H1K7NPo2">vocal folds</a>.<a class="footnote-ref" id="fnref:44" href="#fn:44"><sup>44</sup></a> In normal voice production, exhaled air moves out of the lungs and passes upward through the <a href="/facts/Vocal_tract/RgjPanbg">vocal tract</a>.<a class="footnote-ref" id="fnref:45" href="#fn:45"><sup>45</sup></a> At the level of the larynx, the exhaled air causes the vocal folds to move toward the midline of the tract (a process called adduction). The adducted vocal folds do not close completely but instead remain partially open. The narrow opening between the folds is referred to as the <a href="/facts/Glottis/ClsRRUkM">glottis</a>.<a class="footnote-ref" id="fnref:46" href="#fn:46"><sup>46</sup></a><a class="footnote-ref" id="fnref:47" href="#fn:47"><sup>47</sup></a> As air moves through the glottis, it causes a distortion of the air particles which sets the vocal folds into vibratory motion. It is this vibratory motion that produces phonation or voice.<a class="footnote-ref" id="fnref:48" href="#fn:48"><sup>48</sup></a> In dysphonia, there is an impairment in the ability to produce an appropriate level of phonation. More specifically, it results from an impairment in vocal fold vibration or the nerve supply of the larynx.<a class="footnote-ref" id="fnref:49" href="#fn:49"><sup>49</sup></a> </p> <h2 id="diagnosis">Diagnosis</h2> <p>The assessment and diagnosis of a dysphonic voice is completed by a multidisciplinary team, such as an otolaryngologist (ear, nose and throat doctor) and Speech-Language Pathologist, involving the use of both objective and subjective measures to evaluate the quality of the voice as well as the condition of the vocal fold <a href="/facts/Tissue_(biology)/H7CpML7A">tissue</a> and <a href="/facts/Vibration/sGgDqG71">vibration</a> patterns.<a class="footnote-ref" id="fnref:50" href="#fn:50"><sup>50</sup></a> </p> <h3>Definition</h3> <p>Dysphonia is a broad clinical term which refers to abnormal functioning of the voice.<a class="footnote-ref" id="fnref:51" href="#fn:51"><sup>51</sup></a><a class="footnote-ref" id="fnref:52" href="#fn:52"><sup>52</sup></a> More specifically, a voice can be classified as "dysphonic" when there are abnormalities or impairments in one or more of the following parameters of voice: pitch, loudness, quality, and variability.<a class="footnote-ref" id="fnref:53" href="#fn:53"><sup>53</sup></a> For example, abnormal pitch can be characterized by a voice that is too high or low whereas abnormal loudness can be characterized by a voice that is too quiet or loud.<a class="footnote-ref" id="fnref:54" href="#fn:54"><sup>54</sup></a> Similarly, a voice that has frequent, inappropriate breaks characterizes abnormal quality while a voice that is monotone (i.e., very flat) or inappropriately fluctuates characterizes abnormal variability.<a class="footnote-ref" id="fnref:55" href="#fn:55"><sup>55</sup></a> While hoarseness is used interchangeably with the term dysphonia, it is important to note that the two are not synonymous. Hoarseness is merely a subjective term to explain the perceptual quality (or sound) of a dysphonic voice.<a class="footnote-ref" id="fnref:56" href="#fn:56"><sup>56</sup></a> While hoarseness is a common symptom (or complaint) of dysphonia,<a class="footnote-ref" id="fnref:57" href="#fn:57"><sup>57</sup></a> there are several other signs and symptoms that can be present such as: breathiness, roughness, and dryness. Furthermore, a voice can be classified as dysphonic when it poses problems in the functional or occupational needs of the individual or is inappropriate for their age or sex.<a class="footnote-ref" id="fnref:58" href="#fn:58"><sup>58</sup></a> </p> <h3>Auditory-perceptual measures</h3> <p>Auditory-perceptual measures are the most commonly used tool by clinicians to evaluate the voice quality due to its quick and non-invasive nature.<a class="footnote-ref" id="fnref:59" href="#fn:59"><sup>59</sup></a> Additionally, these measures have been proven to be reliable in a clinical setting.<a class="footnote-ref" id="fnref:60" href="#fn:60"><sup>60</sup></a> Ratings are used to evaluate the quality of a patient's voice for a variety of voice features, including overall severity, roughness, breathiness, strain, loudness and pitch. These evaluations are done during spontaneous speech, sentence or passage reading or sustained vowel productions.<a class="footnote-ref" id="fnref:61" href="#fn:61"><sup>61</sup></a> The GRBAS (Grade, Roughness, Breathiness, Asthenia, Strain) and the CAPE-V (Consensus Auditory Perceptual Evaluation—Voice) are two formal voice rating scales commonly used for this purpose.<a class="footnote-ref" id="fnref:62" href="#fn:62"><sup>62</sup></a> </p> <h3>Vocal fold imaging</h3> <p>Vocal fold imaging techniques are used by clinicians to examine the vocal folds and allows them to detect vocal <a href="/facts/Pathology/U9b18LJG">pathology</a> and assess the quality of the vocal fold vibrations. Laryngeal <a href="/facts/Stroboscope/rGSLFC71">stroboscopy</a> is the primary clinical tool used for this purpose. Laryngeal stroboscopy uses a synchronized flashing light passed through either a rigid or flexible <a href="/facts/Laryngoscopy/tCclGuJ5">laryngoscope</a> to provide an image of the vocal fold motion; the image is created by averaging over several vibratory cycles and is thus not provided in real-time.<a class="footnote-ref" id="fnref:63" href="#fn:63"><sup>63</sup></a> As this technique relies on <a href="/facts/Periodic_function/Sm8lJQsF">periodic</a> vocal fold vibration, it cannot be used in patients with moderate to severe dysphonia.<a class="footnote-ref" id="fnref:64" href="#fn:64"><sup>64</sup></a> High speed digital imaging of the vocal folds (<a href="/facts/Videokymography/g7H3Qvrs">videokymography</a>), another imaging technique, is not subject to the same limitations as laryngeal stroboscopy. A rigid endoscope is used to take images at a rate of 8000 frames per second, and the image is displayed in real time. As well, this technique allows imaging of aperiodic vibrations<a class="footnote-ref" id="fnref:65" href="#fn:65"><sup>65</sup></a> and can thus be used with patients presenting with all severities of dysphonia. </p> <h3>Acoustic measures</h3> <p>Acoustic measures can be used to provide objective measures of vocal function. Signal processing <a href="/facts/Algorithm/fnl5NmRt">algorithms</a> are applied to voice recordings made during sustained <a href="/facts/Phonation/u2IGLdgG">phonation</a> or during spontaneous speech.<a class="footnote-ref" id="fnref:66" href="#fn:66"><sup>66</sup></a> The acoustic parameters which can then be examined include <a href="/facts/Fundamental_frequency/TJBJKHow">fundamental frequency</a>, signal <a href="/facts/Amplitude/aEckuXJM">amplitude</a>, jitter, shimmer, and noise-to-harmonic ratios.<a class="footnote-ref" id="fnref:67" href="#fn:67"><sup>67</sup></a> However, due to limitations imposed by the algorithms employed, these measures cannot be used with patients who exhibit severe dysphonia.<a class="footnote-ref" id="fnref:68" href="#fn:68"><sup>68</sup></a> </p> <h3>Aerodynamic measures</h3> <p><a href="/facts/Aerodynamics/Cn6Lnl3H">Aerodynamic</a> measures of voice include measures of <a href="/facts/Lung_volumes/E28HHIhf">air volume</a>, air flow and sub glottal air pressure. The normal aerodynamic parameters of voice vary considerably among individuals, which leads to a large overlapping range of values between dysphonic and non-dysphonic patients. This limits the use of these measures as a diagnostic tool.<a class="footnote-ref" id="fnref:69" href="#fn:69"><sup>69</sup></a> Nonetheless, they are useful when used in adjunct with other voice assessment measures, or as a tool for monitoring therapeutic effects over time.<a class="footnote-ref" id="fnref:70" href="#fn:70"><sup>70</sup></a> </p> <h2 id="prevention">Prevention</h2> <p>Given that certain occupations are more at risk for developing dysphonia (e.g., teachers) research into prevention studies have been conducted.<a class="footnote-ref" id="fnref:71" href="#fn:71"><sup>71</sup></a> Research into the effectiveness of prevention strategies for dysphonia have yet to produce definitive results, however, research is still ongoing.<a class="footnote-ref" id="fnref:72" href="#fn:72"><sup>72</sup></a><a class="footnote-ref" id="fnref:73" href="#fn:73"><sup>73</sup></a> Primarily, there are two types of vocal training recognized by professionals to help with prevention: direct and indirect. Direct prevention describes efforts to reduce conditions that may serve to increase vocal strain (such as patient education, relaxation strategies, etc.), while indirect prevention strategies refer to changes in the underlying physiological mechanism for voice production (e.g., adjustments to the manner in which vocal fold adduction occurs, respiratory training, shifting postural habits, etc.).<a class="footnote-ref" id="fnref:74" href="#fn:74"><sup>74</sup></a><a class="footnote-ref" id="fnref:75" href="#fn:75"><sup>75</sup></a> </p> <h2 id="treatment">Treatment</h2> <p>Although there is no universal classification of voice problems, voice disorders can be separated into certain categories: organic (structural or neurogenic), functional, neurological (psychogenic) or iatrogenic, for example.<a class="footnote-ref" id="fnref:76" href="#fn:76"><sup>76</sup></a> Depending on the diagnosis and severity of the voice problem, and depending on the category that the voice disorder falls into, there are various treatment methods that can be suggested to the patient. The professional has to keep in mind there is not one universal treatment, but rather the clinical approach must find what the optimal effective course of action for that particular patient is. </p><p>There are three main type of treatments: medical treatments, voice therapy and surgical treatments.<a class="footnote-ref" id="fnref:77" href="#fn:77"><sup>77</sup></a> When necessary, certain voice disorders use a combination of treatment approaches.<a class="footnote-ref" id="fnref:78" href="#fn:78"><sup>78</sup></a> A medical treatment involves the use of botulinum toxin (botox) or anti-reflux medicines, for example. Botox is a key treatment for voice disorders such as Spasmodic Dysphonia.<a class="footnote-ref" id="fnref:79" href="#fn:79"><sup>79</sup></a> Voice therapy is mainly used with patients who have an underlying cause of voice misuse or abuse.<a class="footnote-ref" id="fnref:80" href="#fn:80"><sup>80</sup></a> Laryngologists also recommend this type of treatment to patients who have an organic voice disorder - such as vocal fold nodules, cysts or polyps as well as to treat functional dysphonia.<a class="footnote-ref" id="fnref:81" href="#fn:81"><sup>81</sup></a> Certain surgical treatments can be implemented as well - phono microsurgery (removal of vocal fold lesions performed with a microscope), laryngeal framework surgery (the manipulation of the voice box), as well as injection augmentation (injection of substance to vocal folds to improve closure). Surgical treatments may be recommended for patients having an organic dysphonia.<a class="footnote-ref" id="fnref:82" href="#fn:82"><sup>82</sup></a><a class="footnote-ref" id="fnref:83" href="#fn:83"><sup>83</sup></a> </p><p>A combination of both an indirect treatment method (an approach used to change external factors affecting the vocal folds)<a class="footnote-ref" id="fnref:84" href="#fn:84"><sup>84</sup></a> and a direct <a href="/facts/Voice_therapy/7JWB67YH">treatment</a> method (an approach used where the mechanisms functioning during the use of the vocal folds, such as phonation or respiration, are the main focus)<a class="footnote-ref" id="fnref:85" href="#fn:85"><sup>85</sup></a> may be used to treat dysphonia.<a class="footnote-ref" id="fnref:86" href="#fn:86"><sup>86</sup></a><a class="footnote-ref" id="fnref:87" href="#fn:87"><sup>87</sup></a><a class="footnote-ref" id="fnref:88" href="#fn:88"><sup>88</sup></a><a class="footnote-ref" id="fnref:89" href="#fn:89"><sup>89</sup></a> </p> <h3>Direct therapies</h3> <p>Direct therapies address the physical aspects of vocal production.<a class="footnote-ref" id="fnref:90" href="#fn:90"><sup>90</sup></a> Techniques work to either modify vocal fold contact, manage breathing patterns, and/or change the tension at level of the larynx.<a class="footnote-ref" id="fnref:91" href="#fn:91"><sup>91</sup></a> Notable techniques include, but are not limited to, the yawn-sigh method, optimal pitch, laryngeal manipulation, humming, the accent method, and the <a href="/facts/Lee_Silverman_voice_treatment/RVroHWj1">Lee Silverman Voice Treatment</a>.<a class="footnote-ref" id="fnref:92" href="#fn:92"><sup>92</sup></a><a class="footnote-ref" id="fnref:93" href="#fn:93"><sup>93</sup></a> An example of a direct therapy is circumlaryngeal manual therapy, which has been used to reduce tension and massage hyoid-laryngeal muscles.<a class="footnote-ref" id="fnref:94" href="#fn:94"><sup>94</sup></a> This area is often tense from chronic elevation of the larynx.<a class="footnote-ref" id="fnref:95" href="#fn:95"><sup>95</sup></a> Pressure is applied to these areas as the patient hums or sustains a vowel.<a class="footnote-ref" id="fnref:96" href="#fn:96"><sup>96</sup></a> Traditional voice therapy is often used to treat muscular tension dysphonia.<a class="footnote-ref" id="fnref:97" href="#fn:97"><sup>97</sup></a> </p> <h3>Indirect therapies</h3> <p>Indirect therapies take into account external factors that may influence vocal production.<a class="footnote-ref" id="fnref:98" href="#fn:98"><sup>98</sup></a> This incorporates maintenance of vocal hygiene practices, as well as the prevention of harmful vocal behaviours.<a class="footnote-ref" id="fnref:99" href="#fn:99"><sup>99</sup></a> Vocal hygiene includes adequate hydration of the vocal folds, monitoring the amount of voice use and rest, avoidance of vocal abuse (e.g., shouting, clearing of the throat), and taking into consideration lifestyle choices that may affect vocal health (e.g., smoking, sleeping habits).<a class="footnote-ref" id="fnref:100" href="#fn:100"><sup>100</sup></a> Vocal warm-ups and cool-downs may be employed to improve muscle tension and decrease risk of injury before strenuous vocal activities.<a class="footnote-ref" id="fnref:101" href="#fn:101"><sup>101</sup></a> It should be taken into account that vocal hygiene practices alone are minimally effective in treating dysphonia, and thus should be paired with other therapies.<a class="footnote-ref" id="fnref:102" href="#fn:102"><sup>102</sup></a> </p> <h3>Medication and surgery</h3> <p>Medical and surgical treatments have been recommended to treat organic dysphonias. An effective treatment for <a href="/facts/Spasmodic_dysphonia/4hzAR9AM">spasmodic dysphonia</a> (hoarseness resulting from periodic breaks in phonation due to hyperadduction of the vocal folds) is <a href="/facts/Botulinum_toxin/F2LTx09G">botulinum toxin</a> injection.<a class="footnote-ref" id="fnref:103" href="#fn:103"><sup>103</sup></a><a class="footnote-ref" id="fnref:104" href="#fn:104"><sup>104</sup></a> The toxin acts by blocking <a href="/facts/Acetylcholine/v1d3wRUd">acetylcholine</a> release at the thyro-arytenoid muscle. Although the use of botulinum toxin injections is considered relatively safe, patients' responses to treatment differ in the initial stages; some have reported experiencing swallowing problems and breathy voice quality as a side-effect to the injections.<a class="footnote-ref" id="fnref:105" href="#fn:105"><sup>105</sup></a><a class="footnote-ref" id="fnref:106" href="#fn:106"><sup>106</sup></a> Breathiness may last for a longer period of time for males than females.<a class="footnote-ref" id="fnref:107" href="#fn:107"><sup>107</sup></a> </p><p>Surgeries involve myoectomies of the laryngeal muscles to reduce voice breaks, and laryngoplasties, in which laryngeal cartilage is altered to reduce tension.<a class="footnote-ref" id="fnref:108" href="#fn:108"><sup>108</sup></a> </p> <h2 id="epidemiology">Epidemiology</h2> <p>Dysphonia is a general term for voice impairment that is sometimes used synonymously with the <a href="/facts/Perception/xLK0n2q4">perceptual</a> voice quality of hoarseness.<a class="footnote-ref" id="fnref:109" href="#fn:109"><sup>109</sup></a> It is the reason for 1% of all visits to primary care providers.<a class="footnote-ref" id="fnref:110" href="#fn:110"><sup>110</sup></a> The <a href="/facts/Prevalence/6UTuTGTH">lifetime risk</a> of hoarse voice complaints among primary care patients is 30%.<a class="footnote-ref" id="fnref:111" href="#fn:111"><sup>111</sup></a> Since hoarseness is a general symptom, it is associated with a number of laryngeal diagnoses.<a class="footnote-ref" id="fnref:112" href="#fn:112"><sup>112</sup></a> </p><p>There is an interplay of sex and age differences associated with dysphonia. The <a href="/facts/Point_prevalence/6UTuTGTH">point prevalence</a> of dysphonia in adults under the age of 65 is 6.6%.<a class="footnote-ref" id="fnref:113" href="#fn:113"><sup>113</sup></a> Dysphonia is more common in adult females than males,<a class="footnote-ref" id="fnref:114" href="#fn:114"><sup>114</sup></a><a class="footnote-ref" id="fnref:115" href="#fn:115"><sup>115</sup></a> possibly due to sex-related anatomical differences of the vocal mechanism.<a class="footnote-ref" id="fnref:116" href="#fn:116"><sup>116</sup></a> In childhood, however, dysphonia is more often found in boys than girls.<a class="footnote-ref" id="fnref:117" href="#fn:117"><sup>117</sup></a> As there are no anatomical differences in larynges of boys and girls prior to puberty, it has been proposed that the higher rate of voice impairment found in boys arises from louder social activities, personality factors, or more frequent inappropriate vocal use.<a class="footnote-ref" id="fnref:118" href="#fn:118"><sup>118</sup></a> The most common laryngeal diagnosis among children is <a href="/facts/Vocal_cord_nodule/wNnXc38A">vocal fold nodules</a>,<a class="footnote-ref" id="fnref:119" href="#fn:119"><sup>119</sup></a> a condition known to be associated with vocally damaging behaviours.<a class="footnote-ref" id="fnref:120" href="#fn:120"><sup>120</sup></a> However, a causal relationship has not yet been definitively proven.<a class="footnote-ref" id="fnref:121" href="#fn:121"><sup>121</sup></a> The overall prevalence of dysphonia in children ranges from 3.9% - 23.4%, most commonly affecting children between the ages of 8 - 14.<a class="footnote-ref" id="fnref:122" href="#fn:122"><sup>122</sup></a> Among the elderly, dysphonia is associated with both naturally occurring anatomical and physiological changes as well as higher rates of pathological conditions.<a class="footnote-ref" id="fnref:123" href="#fn:123"><sup>123</sup></a> The point prevalence of dysphonia among the elderly is 29%.<a class="footnote-ref" id="fnref:124" href="#fn:124"><sup>124</sup></a> Findings regarding the prevalence of geriatric dysphonia in the general population are very variable, ranging from 4 - 29.1%.<a class="footnote-ref" id="fnref:125" href="#fn:125"><sup>125</sup></a> This variability is likely due to different <a href="/facts/Methodology/dk5X9Hxx">methodology</a> used in obtaining information from participants.<a class="footnote-ref" id="fnref:126" href="#fn:126"><sup>126</sup></a> The most common laryngeal diagnoses among the elderly are polyps, <a href="/facts/Laryngopharyngeal_reflux/z1gy3yVu">laryngopharyngeal reflux</a>, muscle tension dysphonia, <a href="/facts/Vocal_cord_paresis/mba20hhF">vocal fold paresis</a> or <a href="/facts/Paralysis_of_vocal_cords_and_larynx/mba20hhF">paralysis</a>, vocal fold mass, glottic insufficiency, <a href="/facts/Malignant_lesion/PVW6n1D0">malignant lesions</a>, and neurologic conditions affecting the larynx.<a class="footnote-ref" id="fnref:127" href="#fn:127"><sup>127</sup></a> </p> <h2 id="external-links">External links</h2> <ul><li><a href="http://www.asha.org/public/speech/disorders/voice/">ASHA: Voice Disorders</a></li> <li><a href="http://www.asha.org/Practice-Portal/Clinical-Topics/Voice-Disorders/">ASHA: Clinical Topics - Voice Disorders Overview</a></li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>"Hoarseness". <a href="https://dictionary.cambridge.org/dictionary/english/hoarseness" target="_blank">https://dictionary.cambridge.org/dictionary/english/hoarseness</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>"Hoarseness". NIDCD. 2015-08-18. Retrieved 2017-07-24. <a href="https://www.nidcd.nih.gov/health/hoarseness" target="_blank">https://www.nidcd.nih.gov/health/hoarseness</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Johns MM, Sataloff RT, Merati AL, Rosen CA (August 2010). "Shortfalls of the American Academy of Otolaryngology-Head and Neck Surgery's Clinical practice guideline: Hoarseness (Dysphonia)". Otolaryngology–Head and Neck Surgery. 143 (2): 175–7, discussion 175–80. doi:10.1016/j.otohns.2010.05.026. PMID 20647114. S2CID 22553812. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>"Hoarseness". NIDCD. 2015-08-18. Retrieved 2017-07-24. <a href="https://www.nidcd.nih.gov/health/hoarseness" target="_blank">https://www.nidcd.nih.gov/health/hoarseness</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>"Hoarseness". NIDCD. 2015-08-18. Retrieved 2017-07-24. <a href="https://www.nidcd.nih.gov/health/hoarseness" target="_blank">https://www.nidcd.nih.gov/health/hoarseness</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>"Hoarseness". NIDCD. 2015-08-18. Retrieved 2017-07-24. <a href="https://www.nidcd.nih.gov/health/hoarseness" target="_blank">https://www.nidcd.nih.gov/health/hoarseness</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> <li id="fn:7"><p>"Hoarseness". NIDCD. 2015-08-18. Retrieved 2017-07-24. <a href="https://www.nidcd.nih.gov/health/hoarseness" target="_blank">https://www.nidcd.nih.gov/health/hoarseness</a> <a href="#fnref:7" class="footnote-back-ref">↩</a></p></li> <li id="fn:8"><p>"Hoarseness". NIDCD. 2015-08-18. Retrieved 2017-07-24. <a href="https://www.nidcd.nih.gov/health/hoarseness" target="_blank">https://www.nidcd.nih.gov/health/hoarseness</a> <a href="#fnref:8" class="footnote-back-ref">↩</a></p></li> <li id="fn:9"><p>"Hoarseness". NIDCD. 2015-08-18. Retrieved 2017-07-24. <a href="https://www.nidcd.nih.gov/health/hoarseness" target="_blank">https://www.nidcd.nih.gov/health/hoarseness</a> <a href="#fnref:9" class="footnote-back-ref">↩</a></p></li> <li id="fn:10"><p>Cohen SM, Kim J, Roy N, Asche C, Courey M (February 2012). "Prevalence and causes of dysphonia in a large treatment-seeking population". The Laryngoscope. 122 (2): 343–8. doi:10.1002/lary.22426. PMID 22271658. S2CID 31457683. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:10" class="footnote-back-ref">↩</a></p></li> <li id="fn:11"><p>Williams, N. R. (2003). "Occupational groups at risk for voice disorders: A review of the literature". Occupational Medicine. 53 (7): 456–460. doi:10.1093/occmed/kqg113. PMID 14581643. <a href="https://doi.org/10.1093%2Foccmed%2Fkqg113" target="_blank">https://doi.org/10.1093%2Foccmed%2Fkqg113</a> <a href="#fnref:11" class="footnote-back-ref">↩</a></p></li> <li id="fn:12"><p>Verdolini K, Ramig LO (2001). "Review: occupational risks for voice problems". Logopedics, Phoniatrics, Vocology. 26 (1): 37–46. doi:10.1080/14015430119969. PMID 11432413. S2CID 7436065. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:12" class="footnote-back-ref">↩</a></p></li> <li id="fn:13"><p>"Hoarseness". NIDCD. 2015-08-18. Retrieved 2017-07-24. <a href="https://www.nidcd.nih.gov/health/hoarseness" target="_blank">https://www.nidcd.nih.gov/health/hoarseness</a> <a href="#fnref:13" class="footnote-back-ref">↩</a></p></li> <li id="fn:14"><p>"Hoarseness". NIDCD. 2015-08-18. Retrieved 2017-07-24. <a href="https://www.nidcd.nih.gov/health/hoarseness" target="_blank">https://www.nidcd.nih.gov/health/hoarseness</a> <a href="#fnref:14" class="footnote-back-ref">↩</a></p></li> <li id="fn:15"><p>Aronson AE, Bless DM (2009). Clinical voice disorders. New York: Thieme. pp. 1–5. <a href="#fnref:15" class="footnote-back-ref">↩</a></p></li> <li id="fn:16"><p>Aronson AE, Bless DM (2009). Clinical voice disorders. New York: Thieme. pp. 1–5. <a href="#fnref:16" class="footnote-back-ref">↩</a></p></li> <li id="fn:17"><p>Ludlow CL (June 2009). "Treatment for spasmodic dysphonia: limitations of current approaches". Current Opinion in Otolaryngology & Head and Neck Surgery. 17 (3): 160–5. doi:10.1097/moo.0b013e32832aef6f. PMC 2763389. PMID 19337127. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763389" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763389</a> <a href="#fnref:17" class="footnote-back-ref">↩</a></p></li> <li id="fn:18"><p>Ruotsalainen J, Sellman J, Lehto L, Verbeek J (May 2008). "Systematic review of the treatment of functional dysphonia and prevention of voice disorders". Otolaryngology–Head and Neck Surgery. 138 (5): 557–65. doi:10.1016/j.otohns.2008.01.014. PMID 18439458. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:18" class="footnote-back-ref">↩</a></p></li> <li id="fn:19"><p>"Voice Disorders Overview". American Speech-Language Hearing Association. Retrieved October 2, 2016. <a href="http://www.asha.org/PRPSpecificTopic.aspx?folderid=8589942600§ion=Overview" target="_blank">http://www.asha.org/PRPSpecificTopic.aspx?folderid=8589942600§ion=Overview</a> <a href="#fnref:19" class="footnote-back-ref">↩</a></p></li> <li id="fn:20"><p>"Voice Disorders Overview". American Speech-Language Hearing Association. Retrieved October 2, 2016. <a href="http://www.asha.org/PRPSpecificTopic.aspx?folderid=8589942600§ion=Overview" target="_blank">http://www.asha.org/PRPSpecificTopic.aspx?folderid=8589942600§ion=Overview</a> <a href="#fnref:20" class="footnote-back-ref">↩</a></p></li> <li id="fn:21"><p>"Voice Disorders Overview". American Speech-Language Hearing Association. Retrieved October 2, 2016. <a href="http://www.asha.org/PRPSpecificTopic.aspx?folderid=8589942600§ion=Overview" target="_blank">http://www.asha.org/PRPSpecificTopic.aspx?folderid=8589942600§ion=Overview</a> <a href="#fnref:21" class="footnote-back-ref">↩</a></p></li> <li id="fn:22"><p>Duffy JR, Yorkston KM (2003). "Medical interventions for Spasmodic Dysphonia and some related conditions: A systematic review". Journal of Medical Speech-Language Pathology. 11. <a href="#fnref:22" class="footnote-back-ref">↩</a></p></li> <li id="fn:23"><p>"Voice Disorders Overview". American Speech-Language Hearing Association. Retrieved October 2, 2016. <a href="http://www.asha.org/PRPSpecificTopic.aspx?folderid=8589942600§ion=Overview" target="_blank">http://www.asha.org/PRPSpecificTopic.aspx?folderid=8589942600§ion=Overview</a> <a href="#fnref:23" class="footnote-back-ref">↩</a></p></li> <li id="fn:24"><p>Van Houtte E, Van Lierde K, Claeys S (March 2011). "Pathophysiology and treatment of muscle tension dysphonia: a review of the current knowledge". Journal of Voice. 25 (2): 202–7. doi:10.1016/j.jvoice.2009.10.009. PMID 20400263. <a href="https://biblio.ugent.be/publication/851833/file/1859144" target="_blank">https://biblio.ugent.be/publication/851833/file/1859144</a> <a href="#fnref:24" class="footnote-back-ref">↩</a></p></li> <li id="fn:25"><p>Reiter R, Hoffmann TK, Pickhard A, Brosch S (May 2015). "Hoarseness-causes and treatments". Deutsches Ärzteblatt International. 112 (19): 329–37. doi:10.3238/arztebl.2015.0329. PMC 4458789. PMID 26043420. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458789" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458789</a> <a href="#fnref:25" class="footnote-back-ref">↩</a></p></li> <li id="fn:26"><p>Reiter R, Hoffmann TK, Pickhard A, Brosch S (May 2015). "Hoarseness-causes and treatments". Deutsches Ärzteblatt International. 112 (19): 329–37. doi:10.3238/arztebl.2015.0329. PMC 4458789. PMID 26043420. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458789" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458789</a> <a href="#fnref:26" class="footnote-back-ref">↩</a></p></li> <li id="fn:27"><p>Reiter R, Hoffmann TK, Pickhard A, Brosch S (May 2015). "Hoarseness-causes and treatments". Deutsches Ärzteblatt International. 112 (19): 329–37. doi:10.3238/arztebl.2015.0329. PMC 4458789. PMID 26043420. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458789" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458789</a> <a href="#fnref:27" class="footnote-back-ref">↩</a></p></li> <li id="fn:28"><p>Feierabend RH, Shahram MN (August 2009). "Hoarseness in adults". American Family Physician. 80 (4): 363–70. PMID 19678604. <a href="/wiki/PMID_(identifier)" target="_blank">/wiki/PMID_(identifier)</a> <a href="#fnref:28" class="footnote-back-ref">↩</a></p></li> <li id="fn:29"><p>Pylypowich A, Duff E (2016). "Differentiating the Symptom of Dysphonia". The Journal for Nurse Practitioners. 12 (7): 459–466. doi:10.1016/j.nurpra.2016.04.025. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:29" class="footnote-back-ref">↩</a></p></li> <li id="fn:30"><p>Harries M (2013). "Hoarseness and Voice Disorders". In Ludman HS, Bradley PJ (eds.). ABC of ear, nose, and throat. West Sussex, UK: Wiley-Blackwell. p. 95. <a href="#fnref:30" class="footnote-back-ref">↩</a></p></li> <li id="fn:31"><p>Morris R, Bernard Harmon A (2010). "Describing Voice Disorders". In Damico J, Muller N, Ball MJ (eds.). Handbook of language and speech disorders. Chichester, U.K.: Wiley-Blackwell. pp. 455–473. ISBN 9781405158626. <a href="9781405158626" target="_blank">9781405158626</a> <a href="#fnref:31" class="footnote-back-ref">↩</a></p></li> <li id="fn:32"><p>Dr Pragya Semwal, Dr Shobit Garg Chronic Dissociation Presenting as Dysphonia Plica Ventricularis: An Atypical Presentation. Int. j. med. case reports Vol 6 Issue 3 Jul-Sep 2020 1-3. http://www.ijomcr.net Archived 2021-02-07 at the Wayback Machine <a href="http://www.ijomcr.net" target="_blank">http://www.ijomcr.net</a> <a href="#fnref:32" class="footnote-back-ref">↩</a></p></li> <li id="fn:33"><p>Williams, N. R. (2003). "Occupational groups at risk for voice disorders: A review of the literature". Occupational Medicine. 53 (7): 456–460. doi:10.1093/occmed/kqg113. PMID 14581643. <a href="https://doi.org/10.1093%2Foccmed%2Fkqg113" target="_blank">https://doi.org/10.1093%2Foccmed%2Fkqg113</a> <a href="#fnref:33" class="footnote-back-ref">↩</a></p></li> <li id="fn:34"><p>Verdolini K, Ramig LO (2001). "Review: occupational risks for voice problems". Logopedics, Phoniatrics, Vocology. 26 (1): 37–46. doi:10.1080/14015430119969. PMID 11432413. S2CID 7436065. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:34" class="footnote-back-ref">↩</a></p></li> <li id="fn:35"><p>Cantor Cutiva LC, Vogel I, Burdorf A (March 2013). "Voice disorders in teachers and their associations with work-related factors: a systematic review". Journal of Communication Disorders. 46 (2): 143–55. doi:10.1016/j.jcomdis.2013.01.001. PMID 23415241. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:35" class="footnote-back-ref">↩</a></p></li> <li id="fn:36"><p>Williams, N. R. (2003). "Occupational groups at risk for voice disorders: A review of the literature". Occupational Medicine. 53 (7): 456–460. doi:10.1093/occmed/kqg113. PMID 14581643. <a href="https://doi.org/10.1093%2Foccmed%2Fkqg113" target="_blank">https://doi.org/10.1093%2Foccmed%2Fkqg113</a> <a href="#fnref:36" class="footnote-back-ref">↩</a></p></li> <li id="fn:37"><p>Stachler RJ, Francis DO, Schwartz SR, Damask CC, Digoy GP, Krouse HJ, McCoy SJ, Ouellette DR, Patel RR, Reavis CC, Smith LJ, Smith M, Strode SW, Woo P, Nnacheta LC (March 2018). "Clinical Practice Guideline: Hoarseness (Dysphonia) (Update)". Otolaryngology–Head and Neck Surgery. 158 (1_suppl): S1 – S42. doi:10.1177/0194599817751030. PMID 29494321. <a href="https://doi.org/10.1177%2F0194599817751030" target="_blank">https://doi.org/10.1177%2F0194599817751030</a> <a href="#fnref:37" class="footnote-back-ref">↩</a></p></li> <li id="fn:38"><p>Cantor Cutiva LC, Vogel I, Burdorf A (March 2013). "Voice disorders in teachers and their associations with work-related factors: a systematic review". Journal of Communication Disorders. 46 (2): 143–55. doi:10.1016/j.jcomdis.2013.01.001. 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"Clergyman's Sore Throat". Journal of Singing. 78 (1): 113–117. doi:10.53830/CNLB1302. ISSN 2769-4046. S2CID 239663449. <a href="https://muse.jhu.edu/article/803425" target="_blank">https://muse.jhu.edu/article/803425</a> <a href="#fnref:41" class="footnote-back-ref">↩</a></p></li> <li id="fn:42"><p>Cantor Cutiva LC, Vogel I, Burdorf A (March 2013). "Voice disorders in teachers and their associations with work-related factors: a systematic review". Journal of Communication Disorders. 46 (2): 143–55. doi:10.1016/j.jcomdis.2013.01.001. PMID 23415241. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:42" class="footnote-back-ref">↩</a></p></li> <li id="fn:43"><p>Pestana PM, Vaz-Freitas S, Manso MC (November 2017). "Prevalence of Voice Disorders in Singers: Systematic Review and Meta-Analysis". Journal of Voice. 31 (6): 722–727. doi:10.1016/j.jvoice.2017.02.010. 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