Open problem

<h2 id="see-also">See also</h2>
<ul><li><a href="/facts/Lists_of_unsolved_problems/u9bpE2Xa">Lists of unsolved problems</a> (by major field)</li>
<li><a href="/facts/Hilbert%27s_problems/HaQWIxvV">Hilbert's problems</a></li>
<li><a href="/facts/Millennium_Prize_Problems/WWSB5ddp">Millennium Prize Problems</a></li>
<li><a href="/facts/Conjecture/oPWUb7SF">Conjecture</a></li>
<li>Wikenigma, wiki for open problems</li></ul>

<h2 id="external-links">External links</h2>
<ul><li>Kennedy, Donald; Norman, Colin (2005), <a href="http://www.sciencesignaling.org/cgi/content/summary/sci;309/5731/75">"What Don't We Know?"</a>, <i>Science</i>, 309 (5731): 75, <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1126%2Fscience.309.5731.75">10.1126/science.309.5731.75</a>, <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/15994521">15994521</a></li>
<li>"So much more to know", <i>Science</i>, 309 (5731): 78–102, July 2005, <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1126%2Fscience.309.5731.78b">10.1126/science.309.5731.78b</a>, <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/15994524">15994524</a></li>
<li><a href="http://openproblemgarden.org">Open Problem Garden</a> The collection of open problems in mathematics build on the principle of user editable ("wiki") site</li></ul>

<h2 id="references">References</h2>

<ol>
<li id="fn:1"><p>Faltings, Gerd (July 1995), "The Proof of Fermat's Last Theorem by R. Taylor and A. Wiles" (PDF), Notices of the AMS, 42 (7): 743–746, ISSN 0002-9920 <a href="https://www.ams.org/notices/199507/faltings.pdf" target="_blank">https://www.ams.org/notices/199507/faltings.pdf</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li>
<li id="fn:2"><p>K. Appel and W. Haken (1977), "Every planar map is four colorable. Part I. Discharging", Illinois J. Math 21: 429–490. MR543795 <a href="/wiki/MR_(identifier)" target="_blank">/wiki/MR_(identifier)</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li>
<li id="fn:3"><p>K. Appel, W. Haken, and J. Koch (1977), "Every planar map is four colorable. Part II. Reducibility", Illinois J. Math 21: 491–567. MR543795 <a href="/wiki/MR_(identifier)" target="_blank">/wiki/MR_(identifier)</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li>
<li id="fn:4"><p>Vendruscolo, M.; Najmanovich, R.; Domany, E. (1999), "Protein Folding in Contact Map Space", Physical Review Letters, 82 (3): 656–659, arXiv:cond-mat/9901215, Bibcode:1999PhRvL..82..656V, doi:10.1103/PhysRevLett.82.656, S2CID 6686420 <a href="/wiki/ArXiv_(identifier)" target="_blank">/wiki/ArXiv_(identifier)</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li>
<li id="fn:5"><p>Dill, K.A.; Ozkan, S.B.; Weikl, T.R.; Chodera, J.D.; Voelz, V.A. (2007), "The protein folding problem: when will it be solved?" (PDF), Current Opinion in Structural Biology, 17 (3): 342–346, doi:10.1016/j.sbi.2007.06.001, PMID 17572080, archived from the original (PDF) on 2011-07-20 <a href="https://web.archive.org/web/20110720080804/http://laplace.compbio.ucsf.edu/~jchodera/pubs/pdf/protein-folding-problem.pdf" target="_blank">https://web.archive.org/web/20110720080804/http://laplace.compbio.ucsf.edu/~jchodera/pubs/pdf/protein-folding-problem.pdf</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li>
</ol>

Open problem open-in-new

Open problem