In Buddhism, the three marks of existence are three characteristics (Pali: tilakkhaṇa; Sanskrit: त्रिलक्षण trilakṣaṇa) of all existence and beings, namely anicca (impermanence), dukkha (commonly translated as "suffering" or "cause of suffering", "unsatisfactory", "unease"), and anattā (without a lasting essence). The concept of humans being subject to delusion about the three marks, this delusion resulting in suffering, and removal of that delusion resulting in the end of dukkha, is a central theme in the Buddhist Four Noble Truths, the last of which leads to the Noble Eightfold Path.